Rome2Rio

How to get fromSt. Louis to Florenceby plane, bus (Greyhound), or car

Find Transport to Florence

See all options

There are 5 ways to get from St. Louis to Florence by plane, bus (Greyhound), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Covington

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to Covington (CVG)plane plane STL - CVG
    5h 56m
    $606–956

  2. Bus

    cheapest
    1. Take the bus from St Louis Bus Station to Indianapolis Union Stationbus bus Greyhound US0421
    2. Take the bus from Indianapolis, IN to Greyhound Station Cincinnatibus bus Detroit / ...
    10h 29m
    $53–125

  3. Drive 346.2 mi

    1. Drive from St. Louis to Florencecar car 346.2 mi
    5h 39m
    $64–92

  4. Fly to Blue Grass Airport, drive

    1. Fly from Lambert–St. Louis International Airport (STL) to Blue Grass Airport (LEX)plane plane STL - LEX
    2. Drive from Lexington-Airport-LEX to Florencecar car
    6h 49m
    $196–1,022

  5. Bus via Evansville

    1. Take the bus from St Louis Bus Station to Evansville Bus Stationbus bus
    2. Take the bus from Evansville, IN to Louisville, KYbus bus
    3. Take the bus from Louisville, KY Bus Station to Cincinnati - Downtownbus bus
    10h 48m
    $71–150

St. Louis to Florence by bus

Calendar7Weekly Buses
Duration10h 29mAverage Duration
Ticket$53Cheapest Price
See schedules

Questions & Answers

Map of how to get from St. Louis to Florence.ExpandLaunch map view
  • Distance: 330.4 mi
  • Duration: 5h 56m

What companies run services between St. Louis, MO, USA and Florence, KY, USA?

Southwest Airlines, Delta, and two other airlines fly from Lambert–St. Louis International Airport (STL) to Covington (CVG) hourly. Alternatively, you can take a bus from St Louis Bus Station to Dixie at Turfway via Indianapolis, IN, Greyhound Station Cincinnati, Cincinnati Bus Station, Covington Bus Stop, and Covington Transit Center in around 10h 29m.

Airlines
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers