What is the cheapest way to get from St. Louis to Florence?

The cheapest way to get from St. Louis to Florence is to bus which costs $130 - $260 and takes 17h 20m.

What is the fastest way to get from St. Louis to Florence?

The fastest way to get from St. Louis to Florence is to fly which takes 6h 13m and costs $100 - $550.

Is there a direct bus between St. Louis and Florence?

No, there is no direct bus from St. Louis station to Florence. However, there are services departing from St Louis Bus Station and arriving at Florence via Atlanta. The journey, including transfers, takes approximately 17h 20m.

Is there a direct train between St. Louis and Florence?

No, there is no direct train from St. Louis to Florence station. However, there are services departing from St. Louis and arriving at Florence Station via Chicago Union Station and Petersburg Amtrak Station. The journey, including transfers, takes approximately 33h 4m.

How far is it from St. Louis to Florence?

The distance between St. Louis and Florence is 689 miles. The road distance is 824.9 miles.

How do I travel from St. Louis to Florence without a car?

The best way to get from St. Louis to Florence without a car is to bus which takes 17h 20m and costs $130 - $260.

How long does it take to get from St. Louis to Florence?

It takes approximately 6h 13m to get from St. Louis to Florence, including transfers.

Where do I catch the St. Louis to Florence bus from?

St. Louis to Florence bus services, operated by FlixBus-us, depart from St Louis Bus Station.

Where do I catch the St. Louis to Florence train from?

St. Louis to Florence train services, operated by Amtrak, depart from St. Louis station.

Train, bus or fly from St. Louis to Florence?

The best way to get from St. Louis to Florence is to fly which takes 6h 13m and costs $100 - $550. Alternatively, you can bus, which costs $130 - $260 and takes 17h 20m, you could also train, which costs $460 - $1,000 and takes 33h 4m.

Where does the St. Louis to Florence bus arrive?

St. Louis to Florence bus services, operated by FlixBus-us, arrive at Atlanta Bus Station.

What is the time difference between St. Louis and Florence?

Florence is 1h ahead of St. Louis. It is currently 2:34 AM in St. Louis and 3:34 AM in Florence.

Where does the St. Louis to Florence train arrive?

St. Louis to Florence train services, operated by Amtrak, arrive at Chicago Union Station.

Can I drive from St. Louis to Florence?

Yes, the driving distance between St. Louis to Florence is 825 miles. It takes approximately 13h 48m to drive from St. Louis to Florence.

How do I get a train ticket from St. Louis to Florence?

Book your St. Louis to Florence train tickets online with Omio.

How do I get a bus ticket from St. Louis to Florence?

Book your St. Louis to Florence bus tickets online with Omio and FlixBus.

Where can I stay near Florence?

There are 48+ hotels available in Florence.

St. Louis to Florence - 6 ways to travel via train, plane, bus, and car

How to get fromSt. Louis to Florence

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There are 6 ways to get from St. Louis to Florence by plane, bus (Greyhound, Flixbus), train (Amtrak), car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

Fly to Florence Regional Airport
best
1. Fly from Lambert–St. Louis International Airport (STL) to Florence Regional Airport (FLO)plane STL - FLO
6h 13m
$108–506
Bus
1. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus FlixBus N2521
2. Take the bus from Atlanta to Florencebus Ses 987 / ...
17h 20m
$132–254
Train (Amtrak)
1. Take the train from St. Louis to Chicago Union Stationtrain
2. Take the train from Chicago Union Station to Petersburg Amtrak Stationtrain
3. Take the train from Petersburg Amtrak Station to Florence Stationtrain
33h 4m
$467–964
Drive 820.1 mi
1. Drive from St. Louis to Florencecar 820.1 mi
13h 48m
$150–217
Fly to Myrtle Beach, bus
1. Fly from Lambert–St. Louis International Airport (STL) to Myrtle Beach (MYR)plane STL - MYR
2. Take the bus from Myrtle Beach to Florencebus
6h 13m
Bus via Sumter
1. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus
2. Take the bus from Atlanta to Sumterbus
3. Take the bus from Sumter Bus Stop to Florence Bus Stationbus
18h 50m

St. Louis to Florence by bus

19Weekly Buses

17h 20mAverage Duration

$132Cheapest Price

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Questions & Answers

Map of how to get from St. Louis to Florence.

Launch map view

Distance: 685 mi
Duration: 6h 13m

What companies run services between St. Louis, MO, USA and Florence, SC, USA?

American Airlines and Southwest Airlines fly from Lambert–St. Louis International Airport (STL) to Florence Regional Airport (FLO) twice daily. Alternatively, you can take a bus from St Louis Bus Station to Florence via Atlanta in around 17h 20m.

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