There are 5 ways to get from St. Louis to Florence Station by plane, bus (Flixbus, Amtrak, Greyhound), train (Amtrak), car, or bus (Greyhound, Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Lambert–St. Louis International Airport (STL) to Florence Regional Airport (FLO)plane STL - FLO
6h 13m$102–504Bus via Carbondale
- Take the bus from St Louis Bus Station to Carbondale Intermodal Stationbus
- Take the bus from Carbondale Intermodal Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Florence Bus Stationbus
18h 39m$125–250Train (Amtrak)
- Take the train from St. Louis to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Petersburg Amtrak Stationtrain
- Take the train from Petersburg Amtrak Station to Florence Stationtrain
33h 4m$465–964Drive 820.5 mi
- Drive from St. Louis to Florence Stationcar 820.5 mi
13h 49m$150–217Bus
- Take the bus from St Louis Bus Station to Atlanta Bus Stationbus Greyhound US0186
- Take the bus from Atlanta Bus Station to Florence Bus Stationbus Greyhound US0641S / ...
19h 24m$124–244
St. Louis to Florence Station by train (Amtrak)
Questions & Answers
The cheapest way to get from St. Louis to Florence Station is to bus which costs $120 - $250 and takes 19h 24m.
The fastest way to get from St. Louis to Florence Station is to fly which takes 6h 13m and costs $100 - $550.
No, there is no direct bus from St. Louis station to Florence Station station. However, there are services departing from St Louis Bus Station and arriving at Florence Bus Station via Carbondale Intermodal Station and Atlanta Bus Station. The journey, including transfers, takes approximately 18h 39m.
No, there is no direct train from St. Louis to Florence Station station. However, there are services departing from St. Louis and arriving at Florence Station via Chicago Union Station and Petersburg Amtrak Station. The journey, including transfers, takes approximately 33h 4m.
The distance between St. Louis and Florence Station is 689 miles. The road distance is 825.3 miles.
The best way to get from St. Louis to Florence Station without a car is to bus via Carbondale which takes 18h 39m and costs $120 - $250.
It takes approximately 6h 13m to get from St. Louis to Florence Station, including transfers.
St. Louis to Florence Station bus services, operated by Flixbus USA, depart from St Louis Bus Station.
St. Louis to Florence Station train services, operated by Amtrak, depart from St. Louis station.
The best way to get from St. Louis to Florence Station is to fly which takes 6h 13m and costs $100 - $550. Alternatively, you can bus via Carbondale, which costs $120 - $250 and takes 18h 39m, you could also train, which costs $460 - $1,000 and takes 33h 4m.
What companies run services between St. Louis, MO, USA and Florence Station, SC, USA?
American Airlines and Southwest Airlines fly from Lambert–St. Louis International Airport (STL) to Florence Regional Airport (FLO) twice daily. Alternatively, you can take a bus from St Louis Bus Station to Florence Station via Carbondale Intermodal Station, Atlanta Bus Station, and Florence Bus Station in around 18h 39m.
- Website
- aa.com
Flights from Lambert–St. Louis International Airport to Florence Regional Airport via Charlotte
- Ave. Duration
- 6h 2m
- When
- Every day
- Estimated price
- $90–490
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from St. Louis to Chicago Union Station
- Ave. Duration
- 4h 55m
- Frequency
- 5 times a day
- Estimated price
- $90–190
- Website
- Amtrak
Train from Chicago Union Station to Petersburg Amtrak Station
- Ave. Duration
- 21h 1m
- Frequency
- Once daily
- Estimated price
- $290–600
- Website
- Amtrak
Train from Petersburg Amtrak Station to Florence Station
- Ave. Duration
- 5h 8m
- Frequency
- Twice daily
- Estimated price
- $85–180
- Website
- Amtrak
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from St Louis Bus Station to Carbondale Intermodal Station
- Ave. Duration
- 1h 50m
- Frequency
- Once daily
- Estimated price
- $15–26
- Schedules at
- Flixbus USA
Bus from Carbondale Intermodal Station to Atlanta Bus Station
- Ave. Duration
- 8h 5m
- Frequency
- Once daily
- Estimated price
- $70–120
- Schedules at
- Flixbus USA
Bus from St Louis Bus Station to Atlanta Bus Station
- Ave. Duration
- 10h
- Frequency
- Once daily
- Estimated price
- $90–150
- Schedules at
- Flixbus USA
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from St Louis Bus Station to Carbondale Intermodal Station
- Ave. Duration
- 2h
- Frequency
- Once daily
- Estimated price
- $30–45
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from Atlanta Bus Station to Florence Bus Station
- Ave. Duration
- 6h 20m
- Frequency
- 4 times a day
- Estimated price
- $40–85
- Website
- Greyhound
Bus from St Louis Bus Station to Atlanta Bus Station
- Ave. Duration
- 11h 40m
- Frequency
- Twice daily
- Estimated price
- $80–160
- Website
- Greyhound
Bus from Atlanta Bus Station to Florence Bus Station
- Ave. Duration
- 6h 20m
- Frequency
- 4 times a day
- Estimated price
- $40–85
- Website
- Greyhound
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More Questions & Answers
St. Louis to Florence Station bus services, operated by Flixbus USA, arrive at Carbondale Intermodal Station.
Florence Station is 1h ahead of St. Louis. It is currently 7:42 PM in St. Louis and 8:42 PM in Florence Station.
St. Louis to Florence Station train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between St. Louis to Florence Station is 825 miles. It takes approximately 13h 49m to drive from St. Louis to Florence Station.
Book your St. Louis to Florence Station train tickets online with Omio.
There are 47+ hotels available in Florence Station.