Rome2Rio

How to get fromSt. Louis to Fort Myersby plane, bus (Greyhound, Flixbus), car, taxi, bus, or train

Find Transport to Fort Myers

See all options

There are 9 ways to get from St. Louis to Fort Myers by plane, bus (Greyhound, Flixbus), car, taxi, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Lambert–St. Louis International Airport to Ft. Myers

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to Ft. Myers (RSW)plane plane STL - RSW
    5h 59m
    $136–658

  2. Bus

    1. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Tampa Bus Stationbus bus
    3. Take the bus from Tampa Bus Station to Fort Myers Bus Stopbus bus
    25h 10m
    $182–337

  3. Drive 1,106.3 mi

    1. Drive from St. Louis to Fort Myerscar car 1,106.3 mi
    18h 59m
    $202–292

  4. Fly Midamerica St. Louis Airport to Punta Gorda Airport, taxi

    1. Fly from Midamerica St. Louis Airport (BLV) to Punta Gorda Airport (PGD)plane plane BLV - PGD
    2. Take the taxi from Punta Gorda Airport (PGD) to Fort Myerstaxi taxi
    4h 58m
    $196–556

  5. Fly Lambert–St. Louis International Airport to Sarasota–Bradenton International Airport, bus

    1. Fly from Lambert–St. Louis International Airport (STL) to Sarasota–Bradenton International Airport (SRQ)plane plane STL - SRQ
    2. Take the bus from Sarasota Cattlemen Transfer Center to Fort Myers Bus Stopbus bus
    7h 25m
    $176–824

  6. Fly Lambert–St. Louis International Airport to Fort Lauderdale–Hollywood International Airport, bus

    1. Fly from Lambert–St. Louis International Airport (STL) to Fort Lauderdale–Hollywood International Airport (FLL)plane plane STL - FLL
    2. Take the bus from Fort Lauderdale International Airport to Fort Myers Bus Stopbus bus
    7h 36m
    $524–1,138

  7. Fly Lambert–St. Louis International Airport to Tampa, bus

    1. Fly from Lambert–St. Louis International Airport (STL) to Tampa (TPA)plane plane STL - TPA
    2. Take the bus from Tampa Bus Station to Fort Myers Bus Stopbus bus
    9h
    $446–2,040

  8. Fly Lambert–St. Louis International Airport to Miami International Airport, bus

    1. Fly from Lambert–St. Louis International Airport (STL) to Miami International Airport (MIA)plane plane STL - MIA
    2. Take the bus from Miami Airport Station to Fort Myers Bus Stopbus bus
    8h 41m
    $578–998

  9. Bus, train

    1. Take the bus from St Louis Bus Station to New Orleans Bus Stationbus bus
    2. Take the train from New Orleans Union Passenger Terminal to Gulfport Amtrak Statrain train
    3. Take the bus from Gulfport to Fort Myersbus bus
    33h 6m
    $257–410

St. Louis to Fort Myers by bus

Calendar7Weekly Buses
Duration25h 10mAverage Duration
Ticket$182Cheapest Price
See schedules

Questions & Answers

Map of how to get from St. Louis to Fort Myers.ExpandLaunch map view
  • Distance: 1,008.9 mi
  • Duration: 5h 59m

What companies run services between St. Louis, MO, USA and Fort Myers, FL, USA?

Southwest Airlines, Delta, and American Airlines fly from Lambert–St. Louis International Airport (STL) to Ft. Myers (RSW) every 3 hours. Alternatively, you can take a bus from St Louis Bus Station to Fort Myers Bus Stop via Atlanta Bus Station and Tampa Bus Station in around 25h 10m.

Airlines
Train operators
Bus operators
Other operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers