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How to get fromSt. Louis to Fort Myersby plane, bus (Greyhound, Flixbus), car, taxi, bus, or train

Find Transport to Fort Myers

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There are 9 ways to get from St. Louis to Fort Myers by plane, bus (Greyhound, Flixbus), car, taxi, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Lambert–St. Louis International Airport to Ft. Myers

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to Ft. Myers (RSW)plane plane STL - RSW
    5h 54m
    $126–658

  2. Fly Lambert–St. Louis International Airport to Sarasota–Bradenton International Airport, bus

    cheapest
    1. Fly from Lambert–St. Louis International Airport (STL) to Sarasota–Bradenton International Airport (SRQ)plane plane STL - SRQ
    2. Take the bus from Sarasota Cattlemen Transfer Center to Fort Myers Bus Stopbus bus
    7h 4m
    $110–522

  3. Bus

    1. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Tampa Bus Stationbus bus
    3. Take the bus from Tampa Bus Station to Fort Myers Bus Stopbus bus
    25h 55m
    $178–292

  4. Drive  1,105 mi

    1. Drive from St. Louis to Fort Myerscar car 1,105 mi
    18h 51m
    $202–292

  5. Fly Midamerica St. Louis Airport to Punta Gorda Airport, taxi

    1. Fly from Midamerica St. Louis Airport (BLV) to Punta Gorda Airport (PGD)plane plane BLV - PGD
    2. Take the taxi from Punta Gorda Airport (PGD) to Fort Myerstaxi taxi
    4h 54m
    $180–560

  6. Fly Lambert–St. Louis International Airport to Fort Lauderdale–Hollywood International Airport, bus

    1. Fly from Lambert–St. Louis International Airport (STL) to Fort Lauderdale–Hollywood International Airport (FLL)plane plane STL - FLL
    2. Take the bus from Fort Lauderdale International Airport to Fort Myers Bus Stopbus bus
    7h 46m
    $522–1,132

  7. Fly Lambert–St. Louis International Airport to Tampa, bus

    1. Fly from Lambert–St. Louis International Airport (STL) to Tampa (TPA)plane plane STL - TPA
    2. Take the bus from Tampa Bus Station to Fort Myers Bus Stopbus bus
    8h 58m
    $574–2,034

  8. Fly Lambert–St. Louis International Airport to Miami International Airport, bus

    1. Fly from Lambert–St. Louis International Airport (STL) to Miami International Airport (MIA)plane plane STL - MIA
    2. Take the bus from Miami Airport Station to Fort Myers Bus Stopbus bus
    8h 36m
    $526–992

  9. Bus, train

    1. Take the bus from St Louis Bus Station to New Orleans Bus Stationbus bus
    2. Take the train from New Orleans Union Passenger Terminal to Gulfport Amtrak Statrain train
    3. Take the bus from Gulfport to Fort Myersbus bus
    33h 6m
    $271–389

St. Louis to Fort Myers by bus

Calendar5Weekly Buses
Duration25h 55mAverage Duration
Ticket$178Cheapest Price
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Comparing Your Travel Options

Map of how to get from St. Louis to Fort Myers.ExpandLaunch map view
  • Distance: 1,008.9 mi
  • Duration: 5h 54m

What companies run services between St. Louis, MO, USA and Fort Myers, FL, USA?

Southwest Airlines, Delta, and American Airlines fly from Lambert–St. Louis International Airport (STL) to Ft. Myers (RSW) every 4 hours. Alternatively, you can take a bus from St Louis Bus Station to Fort Myers Bus Stop via Atlanta Bus Station and Tampa Bus Station in around 25h 55m.

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