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How to get fromSt. Louis to Fort Myersby plane, bus (Greyhound, Flixbus), car, bus, taxi, or train

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There are 9 ways to get from St. Louis to Fort Myers by plane, bus (Greyhound, Flixbus), car, bus, taxi, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Lambert–St. Louis International Airport to Ft. Myers

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to Ft. Myers (RSW)plane plane STL - RSW
    5h 59m
    $136–658

  2. Bus

    1. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Tampa Bus Stationbus bus
    3. Take the bus from Tampa Bus Station to Fort Myers Bus Stopbus bus
    25h 5m
    $156–290

  3. Drive  1,106.3 mi

    1. Drive from St. Louis to Fort Myerscar car 1,106.3 mi
    18h 58m
    $202–292

  4. Fly Lambert–St. Louis International Airport to Sarasota–Bradenton International Airport, bus

    1. Fly from Lambert–St. Louis International Airport (STL) to Sarasota–Bradenton International Airport (SRQ)plane plane STL - SRQ
    2. Take the bus from Sarasota Cattlemen Transfer Center to Fort Myers Bus Stopbus bus
    7h 9m
    $174–822

  5. Fly Midamerica St. Louis Airport to Punta Gorda Airport, taxi

    1. Fly from Midamerica St. Louis Airport (BLV) to Punta Gorda Airport (PGD)plane plane BLV - PGD
    2. Take the taxi from Punta Gorda Airport (PGD) to Fort Myerstaxi taxi
    4h 50m
    $186–560

  6. Fly Lambert–St. Louis International Airport to Fort Lauderdale–Hollywood International Airport, bus

    1. Fly from Lambert–St. Louis International Airport (STL) to Fort Lauderdale–Hollywood International Airport (FLL)plane plane STL - FLL
    2. Take the bus from Fort Lauderdale International Airport to Fort Myers Bus Stopbus bus
    7h 36m
    $520–1,132

  7. Fly Lambert–St. Louis International Airport to Tampa, bus

    1. Fly from Lambert–St. Louis International Airport (STL) to Tampa (TPA)plane plane STL - TPA
    2. Take the bus from Tampa Bus Station to Fort Myers Bus Stopbus bus
    8h 58m
    $442–2,034

  8. Fly Lambert–St. Louis International Airport to Miami International Airport, bus

    1. Fly from Lambert–St. Louis International Airport (STL) to Miami International Airport (MIA)plane plane STL - MIA
    2. Take the bus from Miami Airport Station to Fort Myers Bus Stopbus bus
    8h 41m
    $574–988

  9. Bus, train

    1. Take the bus from St Louis Bus Station to New Orleans Bus Stationbus bus
    2. Take the train from New Orleans Union Passenger Terminal to Gulfport Amtrak Statrain train
    3. Take the bus from Gulfport to Fort Myersbus bus
    33h 6m
    $237–378

St. Louis to Fort Myers by bus

Calendar7Weekly Buses
Duration25h 5mAverage Duration
Ticket$156Cheapest Price
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Questions & Answers

Map of how to get from St. Louis to Fort Myers.ExpandLaunch map view
  • Distance: 1,008.9 mi
  • Duration: 5h 59m

What companies run services between St. Louis, MO, USA and Fort Myers, FL, USA?

Southwest Airlines and Delta fly from Lambert–St. Louis International Airport (STL) to Ft. Myers (RSW) every 4 hours. Alternatively, you can take a bus from St Louis Bus Station to Fort Myers Bus Stop via Atlanta Bus Station and Tampa Bus Station in around 25h 5m.

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