Rome2Rio

How to get fromSt. Louis to Framinghamby plane, train (Amtrak), bus (Greyhound, Flixbus), car, or bus (Flixbus)

Find Transport to Framingham

See all options

There are 5 ways to get from St. Louis to Framingham by plane, train (Amtrak), bus (Greyhound, Flixbus), car, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to Boston Logan Airport (BOS)plane plane STL - BOS
    4h 54m
    $372–862

  2. Drive 1,131.2 mi

    cheapest
    1. Drive from St. Louis to Framinghamcar car 1,131.2 mi
    20h 5m
    $207–299

  3. Train (Amtrak)

    1. Take the train from St. Louis to Chicago Union Stationtrain train Lincoln Service / ...
    2. Take the train from Chicago Union Station to Framingham Amtraktrain train Lake Shore Limited
    27h 23m
    $413–885

  4. Bus

    1. Take the bus from St Louis Bus Station to Port Authority Bus Terminalbus bus Greyhound US0421
    2. Take the bus from New York Midtown to Bostonbus bus FlixBus 2610 / ...
    31h 31m
    $208–401

  5. Bus via Auburn Gresham (Flixbus)

    1. Take the bus from St Louis Bus Station to Chicagobus bus
    2. Take the bus from Chicago to New York City Chinatownbus bus
    3. Take the bus from NYC Downtown to Framingham, MAbus bus
    32h 44m
    $228–389

St. Louis to Framingham by train (Amtrak)

Calendar7Weekly Trains
Duration27h 23mAverage Duration
Ticket$413Cheapest Price
See schedules

Questions & Answers

Map of how to get from St. Louis to Framingham.ExpandLaunch map view
  • Distance: 1,080.2 mi
  • Duration: 4h 54m

What companies run services between St. Louis, MO, USA and Framingham, MA, USA?

American Airlines, Southwest Airlines, and Delta fly from Lambert–St. Louis International Airport (STL) to Boston Logan Airport (BOS) every 4 hours. Alternatively, you can take a train from St. Louis to Framingham Amtrak via Chicago Union Station in around 27h 23m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers