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How to get fromSt. Louis to Frederickby plane, bus, bus (Greyhound), train (Amtrak), or car

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There are 6 ways to get from St. Louis to Frederick by plane, bus, bus (Greyhound), train (Amtrak), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Baltimore-Washington International Airport, bus

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to Baltimore-Washington International Airport (BWI)plane plane STL - BWI
    2. Take the bus from Baltimore Airport to Frederick Bus Stationbus bus
    5h 46m
    $182–712

  2. Bus (Greyhound)

    cheapest
    1. Take the bus from St Louis Bus Station to Pittsburgh Intermodal Stationbus bus Greyhound US0421
    2. Take the bus from Pittsburgh Intermodal Station to Frederick Bus Stationbus bus Greyhound US0430 / ...
    19h 10m
    $112–215

  3. Train

    1. Take the train from St. Louis to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Rockville Amtraktrain train
    3. Take the train from ROCKVILLE MARC wb to FREDERICK MARC wbtrain train
    24h 48m
    $278–627

  4. Drive 760.8 mi

    1. Drive from St. Louis to Frederickcar car 760.8 mi
    13h 14m
    $139–201

  5. Fly to Ronald Reagan Washington National Airport, bus

    1. Fly from Lambert–St. Louis International Airport (STL) to Ronald Reagan Washington National Airport (DCA)plane plane STL - DCA
    2. Take the bus from SHADY GROVE & station to Frederick Marc Stationbus bus
    6h 13m
    $138–442

  6. Fly to Washington Dulles International Airport, bus

    1. Fly from Lambert–St. Louis International Airport (STL) to Washington Dulles International Airport (IAD)plane plane STL - IAD
    2. Take the bus from Market St & Harrison St to Frederick Transit Stationbus bus
    6h 40m
    $186–1,028

St. Louis to Frederick by bus (Greyhound)

Calendar21Weekly Buses
Duration19h 10mAverage Duration
Ticket$112Cheapest Price
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Questions & Answers

Map of how to get from St. Louis to Frederick.ExpandLaunch map view
  • Distance: 799.8 mi
  • Duration: 5h 46m

What companies run services between St. Louis, MO, USA and Frederick, MD, USA?

You can take a bus from St Louis Bus Station to Frederick Bus Station via Pittsburgh Intermodal Station in around 19h 10m. Alternatively, you can take a train from St. Louis to FREDERICK MARC wb via Chicago Union Station and ROCKVILLE MARC wb in around 24h 48m.

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