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How to get fromSt. Louis to Gainesvilleby plane, bus (Greyhound, Flixbus), car, or bus

Find Transport to Gainesville

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There are 6 ways to get from St. Louis to Gainesville by plane, bus (Greyhound, Flixbus), car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Gainesville Regional Airport

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to Gainesville Regional Airport (GNV)plane plane STL - GNV
    6h 31m
    $94–484

  2. Bus

    1. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus Greyhound US0186
    2. Take the bus from Atlanta Bus Station to Gainesvillebus bus FlixBus N2401 / ...
    17h 50m
    $128–213

  3. Drive  880 mi

    1. Drive from St. Louis to Gainesvillecar car 880 mi
    14h 36m
    $161–232

  4. Fly to Jacksonville, bus

    1. Fly from Lambert–St. Louis International Airport (STL) to Jacksonville (JAX)plane plane STL - JAX
    2. Take the bus from Jacksonville to Gainesvillebus bus
    7h 33m
    $114–572

  5. Fly to Orlando, bus

    1. Fly from Lambert–St. Louis International Airport (STL) to Orlando (MCO)plane plane STL - MCO
    2. Take the bus from Orlando - RedCoach Station, FL to University of Florida - 1956 Gale Lemerand Drbus bus
    7h 35m
    $214–364

  6. Fly to Tampa, bus

    1. Fly from Lambert–St. Louis International Airport (STL) to Tampa (TPA)plane plane STL - TPA
    2. Take the bus from Tampa Bus Station to Gainesvillebus bus
    9h 23m
    $582–2,050

St. Louis to Gainesville by bus

Calendar12Weekly Buses
Duration17h 50mAverage Duration
Ticket$128Cheapest Price
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Comparing Your Travel Options

Map of how to get from St. Louis to Gainesville.ExpandLaunch map view
  • Distance: 798.3 mi
  • Duration: 6h 31m

What companies run services between St. Louis, MO, USA and Gainesville, FL, USA?

Delta and American Airlines fly from Lambert–St. Louis International Airport (STL) to Gainesville Regional Airport (GNV) every 3 hours. Alternatively, you can take a bus from St Louis Bus Station to Gainesville via Atlanta Bus Station in around 17h 50m.

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Need to know: Greyhound

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