There are 6 ways to get from St. Louis to Grand Central Station by train (Amtrak), bus (Flixbus), car, plane, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train (Amtrak)
best- Take the train from St. Louis to Chicago Union Stationtrain Lincoln Service / ...
5h 8m$90–190Bus (Flixbus)
cheapest- Take the bus from St Louis Bus Station to Chicago Bus Stationbus FlixBus 2510 / ...
6h 17m$50–90Drive 292.3 mi
- Drive from St. Louis to Grand Central Stationcar 292.3 mi
5h 4m$54–78Fly Lambert–St. Louis International Airport to Chicago Midway International Airport
- Fly from Lambert–St. Louis International Airport (STL) to Chicago Midway International Airport (MDW)plane STL - MDW
3h 25m$60–378Fly Lambert–St. Louis International Airport to Chicago O'Hare International Airport
- Fly from Lambert–St. Louis International Airport (STL) to Chicago O'Hare International Airport (ORD)plane STL - ORD
3h 47m$274–708Train to Abraham Lincoln Capital Airport, fly to Chicago O'Hare International Airport
- Take the train from St. Louis to Springfieldtrain
- Fly from Abraham Lincoln Capital Airport (SPI) to Chicago O'Hare International Airport (ORD)plane SPI - ORD
4h 57m$76–314
St. Louis to Grand Central Station by train and foot (Amtrak)
Questions & Answers
The cheapest way to get from St. Louis to Grand Central Station is to bus which costs $50 - $90 and takes 6h 17m.
The fastest way to get from St. Louis to Grand Central Station is to fly which takes 3h 25m and costs $55 - $380.
Yes, there is a direct bus departing from St Louis Bus Station station and arriving at Chicago Bus Station station. Services depart twice daily, and operate every day. The journey takes approximately 6h 5m.
Yes, there is a direct train departing from St. Louis and arriving at Chicago Union Station station. Services depart five times a day, and operate every day. The journey takes approximately 4h 55m.
The distance between St. Louis and Grand Central Station is 283 miles. The road distance is 294 miles.
The best way to get from St. Louis to Grand Central Station without a car is to train which takes 5h 8m and costs $90 - $190.
The train from St. Louis to Chicago Union Station takes 4h 55m including transfers and departs five times a day.
St. Louis to Grand Central Station bus services, operated by Flixbus USA, depart from St Louis Bus Station.
St. Louis to Grand Central Station train services, operated by Amtrak, depart from St. Louis station.
The best way to get from St. Louis to Grand Central Station is to train which takes 5h 8m and costs $90 - $190. Alternatively, you can bus, which costs $50 - $90 and takes 6h 17m, you could also fly, which costs $55 - $380 and takes 3h 25m.
What companies run services between St. Louis, MO, USA and Grand Central Station, IL, USA?
Amtrak operates a train from St. Louis to Chicago Union Station 5 times a day. Tickets cost $90–190 and the journey takes 4h 55m. Alternatively, Flixbus USA operates a bus from St Louis Bus Station to Chicago Bus Station twice daily. Tickets cost $50–90 and the journey takes 6h 5m.
- Website
- southwest.com
Flights from Lambert–St. Louis International Airport to Chicago Midway International Airport
- Ave. Duration
- 1h 5m
- When
- Every day
- Estimated price
- $55–370
- Website
- united.com
Flights from Lambert–St. Louis International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 33m
- When
- Every day
- Estimated price
- $45–310
- Website
- aa.com
Flights from Lambert–St. Louis International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 32m
- When
- Every day
- Estimated price
- $45–310
Flights from Abraham Lincoln Capital Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- $30–230
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from St. Louis to Chicago Union Station
- Ave. Duration
- 4h 55m
- Frequency
- 5 times a day
- Estimated price
- $90–190
- Website
- https://www.amtrak.com/home.html
Train from St. Louis to Springfield
- Ave. Duration
- 1h 38m
- Frequency
- 5 times a day
- Estimated price
- $30–65
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from St Louis Bus Station to Chicago Bus Station
- Ave. Duration
- 6h 5m
- Frequency
- Twice daily
- Estimated price
- $50–90
- Schedules at
- flixbus.com
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More Questions & Answers
St. Louis to Grand Central Station bus services, operated by Flixbus USA, arrive at Chicago Bus Station.
St. Louis to Grand Central Station train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between St. Louis to Grand Central Station is 294 miles. It takes approximately 5h 4m to drive from St. Louis to Grand Central Station.
Book your St. Louis to Grand Central Station train tickets online with Omio.
Book your St. Louis to Grand Central Station bus tickets online with Omio and FlixBus.
There are 1331+ hotels available in Grand Central Station.