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How to get fromSt. Louis to Grayslakeby train (Amtrak), bus (Flixbus), car, plane, train, or bus

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There are 9 ways to get from St. Louis to Grayslake by train (Amtrak), bus (Flixbus), car, plane, train, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from St. Louis to Chicago Union Stationtrain train Lincoln Service / ...
    2. Take the train from Chicago Union Station to Grayslaketrain train Md-N
    6h 58m
    $73–169

  2. Bus (Flixbus)

    cheapest
    1. Take the bus from St Louis Bus Station to Chicago Bus Stationbus bus FlixBus N2521 / ...
    8h 58m
    $56–88

  3. Drive  316.5 mi

    1. Drive from St. Louis to Grayslakecar car 316.5 mi
    5h 35m
    $58–84

  4. Fly Lambert–St. Louis International Airport to Chicago Midway International Airport, train

    1. Fly from Lambert–St. Louis International Airport (STL) to Chicago Midway International Airport (MDW)plane plane STL - MDW
    2. Take the train from Chicago Union Station to Grayslaketrain train
    5h 32m
    $60–364

  5. Fly Lambert–St. Louis International Airport to Chicago O'Hare International Airport, train

    1. Fly from Lambert–St. Louis International Airport (STL) to Chicago O'Hare International Airport (ORD)plane plane STL - ORD
    2. Take the train from Edgebrook to Grayslaketrain train
    5h 27m
    $332–716

  6. Train to Abraham Lincoln Capital Airport, fly to Chicago O'Hare International Airport, train

    1. Take the train from St. Louis to Springfieldtrain train
    2. Fly from Abraham Lincoln Capital Airport (SPI) to Chicago O'Hare International Airport (ORD)plane plane SPI - ORD
    3. Take the train from Edgebrook to Grayslaketrain train
    6h 31m
    $76–315

  7. Fly Lambert–St. Louis International Airport to General Mitchell International Airport, train

    1. Fly from Lambert–St. Louis International Airport (STL) to General Mitchell International Airport (MKE)plane plane STL - MKE
    2. Take the train from Milwaukee to Glenview Amtrak Stationtrain train
    3. Take the train from Glenview to Grayslaketrain train
    6h 40m
    $504–912

  8. Bus to Decatur Airport, fly to Chicago O'Hare International Airport, train

    1. Take the bus from St Louis Bus Station to Decatur Downtown Transportation Centerbus bus
    2. Fly from Decatur Airport (DEC) to Chicago O'Hare International Airport (ORD)plane plane DEC - ORD
    3. Take the train from Edgebrook to Grayslaketrain train
    7h 22m
    $74–291

  9. Bus to Williamson County Regional Airport, fly to Chicago O'Hare International Airport, train

    1. Take the bus from St. Louis to Carbondalebus bus
    2. Fly from Williamson County Regional Airport (MWA) to Chicago O'Hare International Airport (ORD)plane plane MWA - ORD
    3. Take the train from Edgebrook to Grayslaketrain train
    7h 33m
    $134–296

St. Louis to Grayslake by train

Calendar38Weekly Trains
Duration6h 58mAverage Duration
Ticket$73Cheapest Price
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Comparing Your Travel Options

Map of how to get from St. Louis to Grayslake.ExpandLaunch map view
  • Distance: 321.8 mi
  • Duration: 6h 58m

What companies run services between St. Louis, MO, USA and Grayslake, IL, USA?

You can take a train from St. Louis to Grayslake via Chicago Union Station in around 6h 58m. Alternatively, Flixbus USA operates a bus from St Louis Bus Station to Chicago Bus Station twice daily. Tickets cost $45–75 and the journey takes 6h 5m.

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