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How to get fromSt. Louis to Greenevilleby plane, car, bus, train, or taxi

Find Transport to Greeneville

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There are 7 ways to get from St. Louis to Greeneville by plane, car, bus, train, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Mcghee Tyson Airport, drive

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to Mcghee Tyson Airport (TYS)plane plane STL - TYS
    2. Drive from Mcghee Tyson Airport (TYS) to Greenevillecar car
    6h 31m
    $148–874

  2. Drive 519.5 mi

    cheapest
    1. Drive from St. Louis to Greenevillecar car 519.5 mi
    10h 8m
    $95–137

  3. Bus, train, drive

    1. Take the bus from St Louis Bus Station to Indianapolis Union Stationbus bus
    2. Take the train from Indianapolis to Ashland Amtrak Stationtrain train
    3. Take the bus from Ashland to Wythevillebus bus
    4. Take the bus from Wytheville Rural King Parking Lot to Bristol Exit 5 Park & Ride Lotbus bus
    5. Drive from Bristol Exit 5 Park & Ride Lot to Greenevillecar car
    20h 56m
    $184–370

  4. Fly to Tri-Cities Regional Tn/Va Airport, taxi

    1. Fly from Lambert–St. Louis International Airport (STL) to Tri-Cities Regional Tn/Va Airport (TRI)plane plane STL - TRI
    2. Take the taxi from Tri-Cities-Regional-Airport-TRI to Greenevilletaxi taxi
    5h 56m
    $212–782

  5. Fly to Asheville Regional Airport, drive

    1. Fly from Lambert–St. Louis International Airport (STL) to Asheville Regional Airport (AVL)plane plane STL - AVL
    2. Drive from ART Station to Greenevillecar car
    7h 56m
    $98–498

  6. Bus, drive via Nashville

    1. Take the bus from St. Louis to Carbondalebus bus
    2. Take the bus from Carbondale Intermodal Station to Nashville Bus Stationbus bus
    3. Take the bus from Nashville Bus Station to Roanoke Bus Stopbus bus
    4. Take the bus from 3rd St Station Slip D to Exit 118 - Park and Ridebus bus Swb
    5. Take the bus from Christiansburg to Bristol Exit 5 Park & Ride Lotbus bus
    6. Drive from Bristol Exit 5 Park & Ride Lot to Greenevillecar car
    22h 20m
    $138–261

  7. Bus, drive

    1. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Winston Salem(Trans Center)bus bus
    3. Take the bus from Winston Salem(Trans Center) to Asheville, NCbus bus
    4. Drive from Asheville, NC to Greenevillecar car
    23h 55m
    $158–300

Lambert–St. Louis International Airport (STL) to Mcghee Tyson Airport (TYS) flights

Calendar111Weekly Planes
Duration5hAverage Duration
Ticket$137Cheapest Price
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Questions & Answers

Map of how to get from St. Louis to Greeneville.ExpandLaunch map view
  • Distance: 501.5 mi
  • Duration: 6h 31m

What companies run services between St. Louis, MO, USA and Greeneville, TN, USA?

There is no direct connection from St. Louis to Greeneville. However, you can take the train to LAMBERT AIRPORT TERMINAL #1 station, walk to Lambert–St. Louis International Airport (STL) airport, fly to Mcghee Tyson Airport (TYS), then drive to Greeneville. Alternatively, you can take a bus from St Louis Bus Station to Greeneville via Indianapolis Union Station, Indianapolis, Ashland Amtrak Station, Ashland, Wytheville, Wytheville Rural King Parking Lot, and Bristol Exit 5 Park & Ride Lot in around 20h 56m.

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