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How to get fromSt. Louis to Greenvilleby plane, bus (Amtrak, Flixbus, Greyhound), train, bus, car, taxi, or bus (Greyhound, Flixbus)

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There are 7 ways to get from St. Louis to Greenville by plane, bus (Amtrak, Flixbus, Greyhound), train, bus, car, taxi, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Greenville

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to Greenville (PGV)plane plane STL - PGV
    5h 47m
    $110–562

  2. Bus via Carbondale

    1. Take the bus from St. Louis to Carbondalebus bus
    2. Take the bus from Carbondale Intermodal Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Raleigh Bus Stationbus bus
    4. Take the bus from Raleigh Bus Station to Greenville GK Butterfield Trans Ctrbus bus
    22h 20m
    $147–287

  3. Train, bus

    1. Take the train from St. Louis to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Raleigh Union Stationtrain train
    3. Take the bus from Raleigh Bus Station to Greenville GK Butterfield Trans Ctrbus bus
    33h 9m
    $420–906

  4. Drive 856.3 mi

    1. Drive from St. Louis to Greenvillecar car 856.3 mi
    15h 28m
    $157–226

  5. Fly to Albert J. Ellis Airport, taxi

    1. Fly from Lambert–St. Louis International Airport (STL) to Albert J. Ellis Airport (OAJ)plane plane STL - OAJ
    2. Take the taxi from Albert J. Ellis Airport (OAJ) to Greenvilletaxi taxi
    7h 17m
    $238–732

  6. Fly to Coastal Carolina Regional Airport, bus

    1. Fly from Lambert–St. Louis International Airport (STL) to Coastal Carolina Regional Airport (EWN)plane plane STL - EWN
    2. Take the bus from New Bern to Greenville GK Butterfield Trans Ctrbus bus
    8h 11m
    $144–688

  7. Bus

    1. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Raleigh Bus Stationbus bus
    3. Take the bus from Raleigh Bus Station to Greenville GK Butterfield Trans Ctrbus bus
    22h 55m
    $151–292

St. Louis to Greenville by bus

Calendar5Weekly Buses
Duration22h 20mAverage Duration
Ticket$147Cheapest Price
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Questions & Answers

Map of how to get from St. Louis to Greenville.ExpandLaunch map view
  • Distance: 761.7 mi
  • Duration: 5h 47m

What companies run services between St. Louis, MO, USA and Greenville, Pitt County, NC, USA?

American Airlines and Southwest Airlines fly from Lambert–St. Louis International Airport (STL) to Greenville (PGV) twice daily. Alternatively, you can take a bus from St. Louis to Greenville GK Butterfield Trans Ctr via Carbondale Intermodal Station, Atlanta Bus Station, and Raleigh Bus Station in around 22h 20m.

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