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How to get fromSt. Louis to Guanajuatoby plane, bus, bus (Greyhound), train, car, shuttle, or bus (Amtrak, Flixbus)

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There are 9 ways to get from St. Louis to Guanajuato by plane, bus, bus (Greyhound), train, car, shuttle, or bus (Amtrak, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Del Bajío International Airport, bus

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to Del Bajío International Airport (BJX)plane plane STL - BJX
    2. Take the bus from León to Guanajuatobus bus
    11h 6m
    $2,846–13,226

  2. Bus via Oklahoma City

    1. Take the bus from St Louis Bus Station to Oklahoma City Bus Stationbus bus
    2. Take the bus from Oklahoma to Zacatecasbus bus
    3. Take the bus from Zacatecas to Leónbus bus
    4. Take the bus from León to Guanajuatobus bus
    40h 1m
    $6,881–8,796

  3. Train, bus via Nuevo Laredo

    1. Take the train from St. Louis to San Antonio Stationtrain train
    2. Take the bus from San Antonio Station to Nuevo Laredobus bus
    3. Take the bus from Nuevo Laredo to San Luis Potosíbus bus
    4. Take the bus from San Luis Potosí to Leónbus bus
    5. Take the bus from León to Guanajuatobus bus
    42h 47m
    $14,009–20,845

  4. Drive  2,573 km

    1. Drive from St. Louis to Guanajuatocar car 2,573 km
    27h 19m
    $6,485–9,368

  5. Fly to Lic. Jesús Terán Peredo International Airport, shuttle

    1. Fly from Lambert–St. Louis International Airport (STL) to Lic. Jesús Terán Peredo International Airport (AGU)plane plane STL - AGU
    2. Take a shuttle bus from Aguascalientes to Guanajuatoshuttle bus
    10h 57m
    $3,641–17,766

  6. Fly to San Luis Potosí Airport, bus

    1. Fly from Lambert–St. Louis International Airport (STL) to San Luis Potosí Airport (SLP)plane plane STL - SLP
    2. Take the bus from San Luis Potosí to Leónbus bus
    3. Take the bus from León to Guanajuatobus bus
    13h 12m
    $3,511–13,996

  7. Fly to Querétaro Intercontinental Airport, bus

    1. Fly from Lambert–St. Louis International Airport (STL) to Querétaro Intercontinental Airport (QRO)plane plane STL - QRO
    2. Take the bus from Terminal de Autobuses de Querétaro Acceso 1 to Guanajuatobus bus
    13h 23m
    $3,491–14,896

  8. Bus

    1. Take the bus from St. Louis to Carbondalebus bus
    2. Take the bus from Marathon Gas Station - Marion to Tornado Bus Co - San Luis de la Pazbus bus
    3. Take the bus from San Luis de la Paz to Dolores Hidalgobus bus
    4. Take the bus from Dolores Hidalgo to Guanajuatobus bus
    41h 54m
    $5,455–7,255

  9. Train, bus

    1. Take the train from St. Louis to San Marcos Amtraktrain train
    2. Take the bus from San Marcos to San Luis Potosíbus bus
    3. Take the bus from San Luis Potosí to Leónbus bus
    4. Take the bus from León to Guanajuatobus bus
    46h 6m
    $12,459–18,415

Lambert–St. Louis International Airport (STL) to Del Bajío International Airport (BJX) flights

Calendar53Weekly Planes
Duration6h 57mAverage Duration
Ticket$2,700Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from St. Louis to Guanajuato.ExpandLaunch map view
  • Distance: 2,343.3 km
  • Duration: 11h 6m

What companies run services between St. Louis, MO, USA and Guanajuato, Mexico?

You can take a bus from St Louis Bus Station to Guanajuato via Oklahoma City Bus Station, Oklahoma, Zacatecas, and León in around 40h 1m.

Airlines
Train operators
Bus operators

Want to know more about travelling around Mexico

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