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How to get fromSt. Louis to Guelphby plane, train, train (Amtrak), bus (Greyhound, Flixbus), car, bus, or shuttle

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There are 9 ways to get from St. Louis to Guelph by plane, train, train (Amtrak), bus (Greyhound, Flixbus), car, bus, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Toronto Pearson International Airport, train

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to Toronto Pearson International Airport (YYZ)plane plane STL - YYZ
    2. Take the train from Bramalea GO to Guelph Central GOtrain train
    6h 59m
    $118–622

  2. Train

    1. Take the train from St. Louis to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Port Huron Stationtrain train
    3. Take the train from Sarnia to Guelphtrain train
    17h 26m
    $256–757

  3. Bus

    1. Take the bus from St Louis Bus Station to Indianapolis Union Stationbus bus
    2. Take the bus from Indianapolis, IN to Detroit, MIbus bus
    3. Take the bus from Detroit Bus Station to Kitchenerbus bus
    18h 15m
    $132–255

  4. Drive  1,126.8 km

    1. Drive from St. Louis to Guelphcar car 1,126.8 km
    12h 1m
    $228–330

  5. Fly to Toronto Island Airport, train

    1. Fly from Lambert–St. Louis International Airport (STL) to Toronto Island Airport (YTZ)plane plane STL - YTZ
    2. Take the train from Union Station GO to Guelph Central GOtrain train
    9h 40m
    $128–623

  6. Fly to Buffalo Niagara International Airport, bus

    1. Fly from Lambert–St. Louis International Airport (STL) to Buffalo Niagara International Airport (BUF)plane plane STL - BUF
    2. Take the bus from Buffalo to Mississaugabus bus
    3. Take the bus from Winston Churchill Transitway Station to Guelph Central GO Busbus bus
    11h 10m
    $205–1,047

  7. Fly to London International Airport, train

    1. Fly from Lambert–St. Louis International Airport (STL) to London International Airport (YXU)plane plane STL - YXU
    2. Take the train from London to Guelphtrain train
    11h 59m
    $281–1,630

  8. Fly to Detroit, shuttle, train

    1. Fly from Lambert–St. Louis International Airport (STL) to Detroit (DTW)plane plane STL - DTW
    2. Take a shuttle bus from Detroit Airport to London, ON - 105, Wharncliffe Road South, Manor Parkshuttle bus
    3. Take the train from London to Guelphtrain train
    10h 55m
    $1,041–1,757

  9. Train, bus

    1. Take the train from St. Louis to Chicago Union Stationtrain train
    2. Take the bus from Chicago Union Station to Port Huron Stationbus bus
    3. Take the train from Sarnia to Guelphtrain train
    17h 26m
    $256–657

St. Louis to Guelph by train and car

Calendar7Weekly Services
Duration17h 26mAverage Duration
Ticket$256Cheapest Price
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Comparing Your Travel Options

Map of how to get from St. Louis to Guelph.ExpandLaunch map view
  • Distance: 1,136.1 km
  • Duration: 6h 59m

What companies run services between St. Louis, MO, USA and Guelph, ON, Canada?

You can take a train from St. Louis to Guelph via Chicago Union Station, Port Huron Station, and Sarnia in around 17h 26m. Alternatively, you can take a bus from St Louis Bus Station to Guelph via Indianapolis, IN, Detroit Bus Station, and Kitchener in around 18h 15m.

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