Rome2Rio

How to get fromSt. Louis to Harrisburg, Paby plane, bus (Greyhound), train (Amtrak), car, or train

Find Transport to Harrisburg, Pa

See all options

There are 5 ways to get from St. Louis to Harrisburg, Pa by plane, bus (Greyhound), train (Amtrak), car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Harrisburg International Airport

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to Harrisburg International Airport (MDT)plane plane STL - MDT
    6h 30m
    $104–554

  2. Bus

    1. Take the bus from St Louis Bus Station to Harrisburg Bus Stationbus bus Greyhound US0421
    19h 20m
    $120–240

  3. Train (Amtrak)

    1. Take the train from St. Louis to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Pittsburgh Amtrak Stationtrain train
    3. Take the train from Pittsburgh Amtrak Station to Harrisburgtrain train
    21h 45m
    $322–675

  4. Drive 778.6 mi

    1. Drive from St. Louis to Harrisburg, Pacar car 778.6 mi
    13h 23m
    $143–206

  5. Fly to Philadelphia International Airport, train

    1. Fly from Lambert–St. Louis International Airport (STL) to Philadelphia International Airport (PHL)plane plane STL - PHL
    2. Take the train from 30th Street Station to Harrisburgtrain train
    7h 12m
    $196–1,176

St. Louis to Harrisburg, Pa by bus

Calendar42Weekly Buses
Duration19h 20mAverage Duration
Ticket$120Cheapest Price
See schedules

Questions & Answers

Map of how to get from St. Louis to Harrisburg, Pa.ExpandLaunch map view
  • Distance: 756.6 mi
  • Duration: 6h 30m

What companies run services between St. Louis, MO, USA and Harrisburg, Pa, PA, USA?

Delta, American Airlines, and United Airlines fly from Lambert–St. Louis International Airport (STL) to Harrisburg International Airport (MDT) hourly. Alternatively, Greyhound-us operates a bus from St Louis Bus Station to Harrisburg Bus Station 3 times a day, and the journey takes 19h 20m. Greyhound USA also services this route 3 times a day.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers