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How to get fromSt. Louis to Iowa Cityby train, bus, bus (Greyhound), car, or plane

Find Transport to Iowa City

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There are 5 ways to get from St. Louis to Iowa City by train, bus, bus (Greyhound), car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, bus

    best
    1. Take the train from St. Louis to Chicago Union Stationtrain train Lincoln Service / ...
    2. Take the bus from Chicago Bus Station to Iowa Citybus bus Greyhound US0123S / ...
    10h 19m
    $109–231

  2. Drive 259.6 mi

    cheapest
    1. Drive from St. Louis to Iowa Citycar car 259.6 mi
    4h 39m
    $48–69

  3. Bus (Greyhound)

    1. Take the bus from St Louis Bus Station to Des Moinesbus bus Greyhound US0153S
    2. Take the bus from Des Moines to Iowa Citybus bus Greyhound US0123S / ...
    11h 35m
    $74–141

  4. Fly to The Eastern Iowa Airport, bus

    1. Fly from Lambert–St. Louis International Airport (STL) to The Eastern Iowa Airport (CID)plane plane STL - CID
    2. Take the bus from GTC Bay 9 to Court St Transportation Centerbus bus
    8h 35m

  5. Fly to Quad City International Airport, bus

    1. Fly from Lambert–St. Louis International Airport (STL) to Quad City International Airport (MLI)plane plane STL - MLI
    2. Take the bus from Moline Center Station to Iowa Citybus bus
    8h 43m
    $76–430

St. Louis to Iowa City by train, foot, and bus

Calendar14Weekly Services
Duration10h 19mAverage Duration
Ticket$109Cheapest Price
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Questions & Answers

Map of how to get from St. Louis to Iowa City.ExpandLaunch map view
  • Distance: 504 mi
  • Duration: 10h 19m

What companies run services between St. Louis, MO, USA and Iowa City, IA, USA?

You can take a bus from St Louis Bus Station to Iowa City via Des Moines in around 11h 35m.

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