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How to get fromSt. Louis to Jefferson Cityby plane, taxi, bus (Greyhound, Flixbus), car, or bus (Amtrak, Flixbus, Greyhound)

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There are 6 ways to get from St. Louis to Jefferson City by plane, taxi, bus (Greyhound, Flixbus), car, or bus (Amtrak, Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Mcghee Tyson Airport, taxi

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to Mcghee Tyson Airport (TYS)plane plane STL - TYS
    2. Take the taxi from Mcghee Tyson Airport (TYS) to Jefferson Citytaxi taxi
    6h 24m
    $312–1,072

  2. Drive 508.8 mi

    cheapest
    1. Drive from St. Louis to Jefferson Citycar car 508.8 mi
    8h 33m
    $93–135

  3. Bus

    1. Take the bus from St Louis Bus Station to Nashville Bus Stationbus bus Greyhound US0186 / ...
    2. Take the bus from Nashville Bus Station to Knoxville Area Transit Bus Stopbus bus Greyhound US0600
    11h 23m
    $174–275

  4. Fly to Tri-Cities Regional Tn/Va Airport, drive

    1. Fly from Lambert–St. Louis International Airport (STL) to Tri-Cities Regional Tn/Va Airport (TRI)plane plane STL - TRI
    2. Drive from Tri-Cities-Regional-Airport-TRI to Jefferson Citycar car
    6h 24m
    $126–672

  5. Fly to Asheville Regional Airport, drive

    1. Fly from Lambert–St. Louis International Airport (STL) to Asheville Regional Airport (AVL)plane plane STL - AVL
    2. Drive from Asheville-Airport-AVL to Jefferson Citycar car
    7h 4m
    $104–508

  6. Bus via Carbondale

    1. Take the bus from St. Louis to Carbondalebus bus
    2. Take the bus from Carbondale Intermodal Station to Nashville Bus Stationbus bus
    3. Take the bus from Nashville Bus Station to Knoxville Area Transit Bus Stopbus bus
    11h 43m
    $172–285

Lambert–St. Louis International Airport (STL) to Mcghee Tyson Airport (TYS) flights

Calendar112Weekly Planes
Duration5h 2mAverage Duration
Ticket$137Cheapest Price
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Questions & Answers

Map of how to get from St. Louis to Jefferson City.ExpandLaunch map view
  • Distance: 460.1 mi
  • Duration: 6h 24m

What companies run services between St. Louis, MO, USA and Jefferson City, TN, USA?

You can take a bus from St Louis Bus Station to Jefferson City via Nashville Bus Station and Knoxville Area Transit Bus Stop in around 11h 23m.

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