There are 3 ways to get from St. Louis to Key West (Island) by plane, bus (Flixbus, Greyhound), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Lambert–St. Louis International Airport (STL) to Key West International Airport (EYW)plane STL - EYW
6h 7m$92–442Bus
- Take the bus from St Louis Bus Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Miami Airport Stationbus
- Take the bus from Miami Airport Station to Key West Airportbus
30h 10m$214–381Drive 1,350.2 mi
- Drive from St. Louis to Key Westcar 1,350.2 mi
23h 43m$247–356
St. Louis to Key West (Island) by bus
Comparing Your Travel Options
The cheapest way to get from St. Louis to Key West (Island) is to fly which costs $90 - $450 and takes 6h 7m.
The fastest way to get from St. Louis to Key West (Island) is to fly which takes 6h 7m and costs $90 - $450.
No, there is no direct bus from St. Louis station to Key West (Island). However, there are services departing from St Louis Bus Station and arriving at Key West Airport via Atlanta Bus Station and Miami Airport Station. The journey, including transfers, takes approximately 30h 10m.
The distance between St. Louis and Key West (Island) is 1123 miles. The road distance is 1358.1 miles.
The best way to get from St. Louis to Key West (Island) without a car is to bus which takes 30h 10m and costs $210 - $390.
It takes approximately 6h 7m to get from St. Louis to Key West (Island), including transfers.
St. Louis to Key West (Island) bus services, operated by Flixbus USA, depart from St Louis Bus Station.
The best way to get from St. Louis to Key West (Island) is to fly which takes 6h 7m and costs $90 - $450. Alternatively, you can bus, which costs $210 - $390 and takes 30h 10m.
St. Louis to Key West (Island) bus services, operated by Flixbus USA, arrive at Atlanta Bus Station.
Key West (Island) is 1h ahead of St. Louis. It is currently 2:22 PM in St. Louis and 3:22 PM in Key West (Island).
What companies run services between St. Louis, MO, USA and Key West (Island), FL, USA?
Delta and American Airlines fly from Lambert–St. Louis International Airport (STL) to Key West International Airport (EYW) every 3 hours. Alternatively, you can take a bus from St Louis Bus Station to Key West Airport via Atlanta Bus Station and Miami Airport Station in around 30h 10m.
- Website
- aa.com
Flights from Lambert–St. Louis International Airport to Key West International Airport via Miami
- Ave. Duration
- 5h 6m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $90–450
Flights from Lambert–St. Louis International Airport to Key West International Airport via Charlotte
- Ave. Duration
- 5h 26m
- When
- Every day
- Estimated price
- $100–470
Flights from Lambert–St. Louis International Airport to Key West International Airport via Dallas/Ft.Worth
- Ave. Duration
- 5h 42m
- When
- Monday to Saturday
- Estimated price
- $110–550
- Website
- delta.com
Flights from Lambert–St. Louis International Airport to Key West International Airport via Atlanta
- Ave. Duration
- 5h 10m
- When
- Every day
- Estimated price
- $90–440
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from St Louis Bus Station to Atlanta Bus Station
- Ave. Duration
- 10h 10m
- Frequency
- 5 times a week
- Estimated price
- $85–130
- Schedules at
- Flixbus USA
Bus from Atlanta Bus Station to Miami Airport Station
- Ave. Duration
- 13h 30m
- Frequency
- Once daily
- Estimated price
- $100–160
- Schedules at
- Flixbus USA
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from St Louis Bus Station to Atlanta Bus Station
- Ave. Duration
- 11h 40m
- Frequency
- Once daily
- Estimated price
- $95–150
- Website
- Greyhound
Bus from Atlanta Bus Station to Miami Airport Station
- Ave. Duration
- 17h 20m
- Frequency
- Once daily
- Estimated price
- $120–190
- Website
- Greyhound
Bus from Miami Airport Station to Key West Airport
- Ave. Duration
- 4h 30m
- Frequency
- 3 times a day
- Estimated price
- $27–45
- Website
- Greyhound
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Booking & Getting There
Yes, the driving distance between St. Louis to Key West (Island) is 1358 miles. It takes approximately 23h 43m to drive from St. Louis to Key West (Island).
Book your St. Louis to Key West (Island) bus tickets online with Omio and FlixBus.
There are 965+ hotels available in Key West (Island).