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How to get fromSt. Louis to Knoxby train, taxi, bus (Greyhound), car, plane, or bus

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There are 8 ways to get from St. Louis to Knox by train, taxi, bus (Greyhound), car, plane, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, taxi

    best
    1. Take the train from St. Louis to Chicago Union Stationtrain train
    2. Take the train from Van Buren St. to Beverly Shorestrain train
    3. Take the taxi from Beverly Shores to Knoxtaxi taxi
    7h 41m
    $297–414

  2. Drive  315.9 mi

    cheapest
    1. Drive from St. Louis to Knoxcar car 315.9 mi
    6h 3m
    $58–84

  3. Bus

    1. Take the bus from St Louis Bus Station to Indianapolis Union Stationbus bus Greyhound US0421
    2. Take the bus from Indianapolis Union Station to Plymouth - Pilot Travel Centerbus bus South Bend
    8h 57m
    $149–274

  4. Fly Lambert–St. Louis International Airport to South Bend, taxi

    1. Fly from Lambert–St. Louis International Airport (STL) to South Bend (SBN)plane plane STL - SBN
    2. Take the taxi from South-Bend-Airport-SBN to Knoxtaxi taxi
    6h 14m
    $178–532

  5. Bus, taxi

    1. Take the bus from St Louis Bus Station to Chicago Bus Stationbus bus
    2. Take the bus from Chicago to La Paz Plymouthbus bus
    3. Take the taxi from La Paz Plymouth to Knoxtaxi taxi
    9h 58m
    $150–230

  6. Fly Lambert–St. Louis International Airport to Chicago Midway International Airport, train, taxi

    1. Fly from Lambert–St. Louis International Airport (STL) to Chicago Midway International Airport (MDW)plane plane STL - MDW
    2. Take the train from Museum Campus/11th St. to Beverly Shorestrain train
    3. Take the taxi from Beverly Shores to Knoxtaxi taxi
    5h 51m
    $194–550

  7. Fly Lambert–St. Louis International Airport to Chicago O'Hare International Airport, train, taxi

    1. Fly from Lambert–St. Louis International Airport (STL) to Chicago O'Hare International Airport (ORD)plane plane STL - ORD
    2. Take the train from Van Buren St. to Beverly Shorestrain train
    3. Take the taxi from Beverly Shores to Knoxtaxi taxi
    6h 19m
    $464–880

  8. Train to Abraham Lincoln Capital Airport, fly to Chicago O'Hare International Airport, train, taxi

    1. Take the train from St. Louis to Springfieldtrain train
    2. Fly from Abraham Lincoln Capital Airport (SPI) to Chicago O'Hare International Airport (ORD)plane plane SPI - ORD
    3. Take the train from Van Buren St. to Beverly Shorestrain train
    4. Take the taxi from Beverly Shores to Knoxtaxi taxi
    7h 32m
    $238–504

Lambert–St. Louis International Airport (STL) to South Bend (SBN) flights

Calendar125Weekly Planes
Duration5h 15mAverage Duration
Ticket$58Cheapest Price
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Comparing Your Travel Options

Map of how to get from St. Louis to Knox.ExpandLaunch map view
  • Distance: 373.5 mi
  • Duration: 7h 41m

What companies run services between St. Louis, MO, USA and Knox, Starke County, IN, USA?

You can take a bus from St Louis Bus Station to Knox via Indianapolis Union Station and Plymouth - Pilot Travel Center in around 8h 57m.

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