There are 5 ways to get from St. Louis to Lexington by bus (Flixbus, Greyhound), car, plane, bus, or taxi
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from St Louis Bus Station to Memphis Bus Stationbus FlixBus 2510
- Take the bus from Memphis Bus Station to Jacksonbus Greyhound US0135 / ...
7h 48m$127–193Drive 264.4 mi
cheapest- Drive from St. Louis to Lexingtoncar 264.4 mi
5h 17m$49–70Fly to Nashville, bus
- Fly from Lambert–St. Louis International Airport (STL) to Nashville (BNA)plane STL - BNA
- Take the bus from Nashville Bus Station to Jacksonbus
6h 53m$174–730Fly to Memphis, bus
- Fly from Lambert–St. Louis International Airport (STL) to Memphis (MEM)plane STL - MEM
- Take the bus from Memphis Bus Station to Jacksonbus
8h 58m$216–864Fly to Mc Kellar-Sipes Regional Airport, taxi
- Fly from Lambert–St. Louis International Airport (STL) to Mc Kellar-Sipes Regional Airport (MKL)plane STL - MKL
- Take the taxi from Mc Kellar-Sipes Regional Airport (MKL) to Lexingtontaxi
6h 13m$202–682
Lambert–St. Louis International Airport (STL) to Nashville (BNA) flights
Questions & Answers
The cheapest way to get from St. Louis to Lexington is to drive which costs $45 - $70 and takes 5h 17m.
The fastest way to get from St. Louis to Lexington is to drive which takes 5h 17m and costs $45 - $70.
No, there is no direct bus from St. Louis station to Lexington. However, there are services departing from St Louis Bus Station and arriving at Jackson via Memphis Bus Station. The journey, including transfers, takes approximately 7h 48m.
The distance between St. Louis and Lexington is 404 miles. The road distance is 266 miles.
The best way to get from St. Louis to Lexington without a car is to bus which takes 7h 48m and costs $120 - $200.
It takes approximately 7h 48m to get from St. Louis to Lexington, including transfers.
St. Louis to Lexington bus services, operated by Flixbus USA, depart from St Louis Bus Station.
St. Louis to Lexington bus services, operated by Flixbus USA, arrive at Memphis Bus Station.
Yes, the driving distance between St. Louis to Lexington is 266 miles. It takes approximately 5h 17m to drive from St. Louis to Lexington.
There are eight+ hotels available in Lexington.
What companies run services between St. Louis, MO, USA and Lexington, TN, USA?
You can take a bus from St Louis Bus Station to Lexington via Memphis Bus Station and Jackson in around 7h 48m.
- Website
- southwest.com
Flights from Lambert–St. Louis International Airport to Nashville
- Ave. Duration
- 1h 10m
- When
- Every day
- Estimated price
- $65–420
Flights from Lambert–St. Louis International Airport to Memphis via Nashville
- Ave. Duration
- 3h 12m
- When
- Sunday, Monday, Thursday, and Friday
- Estimated price
- $130–750
Flights from Lambert–St. Louis International Airport to Memphis via Dallas
- Ave. Duration
- 5h 10m
- When
- Every day
- Estimated price
- $200–1,000
Flights from Lambert–St. Louis International Airport to Memphis via Chicago Midway
- Ave. Duration
- 5h 3m
- When
- Every day
- Estimated price
- $170–900
- Website
- delta.com
Flights from Lambert–St. Louis International Airport to Memphis via Atlanta
- Ave. Duration
- 4h 47m
- When
- Every day
- Estimated price
- $180–950
- Website
- united.com
Flights from Lambert–St. Louis International Airport to Memphis via Chicago O'Hare
- Ave. Duration
- 4h 55m
- When
- Every day
- Estimated price
- $170–900
- Website
- aa.com
Flights from Lambert–St. Louis International Airport to Memphis via Chicago O'Hare
- Ave. Duration
- 5h 27m
- When
- Every day
- Estimated price
- $170–900
- Website
- keylimeair.com
Flights from Lambert–St. Louis International Airport to Mc Kellar-Sipes Regional Airport via Atlanta
- Ave. Duration
- 4h
- When
- Monday, Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $100–550
Flights from Lambert–St. Louis International Airport to Mc Kellar-Sipes Regional Airport via Chicago O'Hare
- Ave. Duration
- 5h 5m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $260–950
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from St Louis Bus Station to Memphis Bus Station
- Ave. Duration
- 4h 45m
- Frequency
- Once daily
- Estimated price
- $45–80
- Schedules at
- flixbus.com
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- greyhound.com
Bus from St Louis Bus Station to Memphis Bus Station
- Ave. Duration
- 5h 30m
- Frequency
- Once daily
- Estimated price
- $40–85
- Website
- https://www.greyhound.com/
Bus from Memphis Bus Station to Jackson
- Ave. Duration
- 1h 30m
- Frequency
- 4 times a day
- Estimated price
- $13–25
- Website
- https://www.greyhound.com/
Bus from Nashville Bus Station to Jackson
- Ave. Duration
- 2h
- Frequency
- 3 times a day
- Estimated price
- $19–40
- Website
- https://www.greyhound.com/
Bus from Memphis Bus Station to Jackson
- Ave. Duration
- 1h 30m
- Frequency
- 4 times a day
- Estimated price
- $13–25
- Website
- https://www.greyhound.com/
- Ave. Duration
- 42 min
- Estimated price
- $100–130
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