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How to get fromSt. Louis to Louisianaby plane, bus (Greyhound), bus, train, or car

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There are 6 ways to get from St. Louis to Louisiana by plane, bus (Greyhound), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Louis Armstrong New Orleans International Airport

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to Louis Armstrong New Orleans International Airport (MSY)plane plane STL - MSY
    3h 16m
    $402–902

  2. Bus (Greyhound)

    cheapest
    1. Take the bus from St Louis Bus Station to New Orleans Bus Stationbus bus Greyhound US1173
    16h 50m
    $110–220

  3. Bus, train

    1. Take the bus from St. Louis to Carbondalebus bus Amtrak Thruway Connecting Service
    2. Take the train from Carbondale to New Orleans Union Passenger Terminaltrain train City of New Orleans
    16h 53m
    $215–456

  4. Drive 676 mi

    1. Drive from St. Louis to New Orleanscar car 676 mi
    10h 58m
    $124–179

  5. Fly to Lafayette Regional Airport

    1. Fly from Lambert–St. Louis International Airport (STL) to Lafayette Regional Airport (LFT)plane plane STL - LFT
    5h 47m
    $124–566

  6. Fly to Lake Charles Regional Airport

    1. Fly from Lambert–St. Louis International Airport (STL) to Lake Charles Regional Airport (LCH)plane plane STL - LCH
    6h 2m
    $114–566

St. Louis to Louisiana by bus (Greyhound)

Calendar7Weekly Buses
Duration16h 50mAverage Duration
Ticket$110Cheapest Price
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Questions & Answers

Map of how to get from St. Louis to Louisiana.ExpandLaunch map view
  • Distance: 619.1 mi
  • Duration: 3h 16m

What companies run services between St. Louis, MO, USA and Louisiana, USA?

Southwest Airlines flies from Lambert–St. Louis International Airport (STL) to Louis Armstrong New Orleans International Airport (MSY) 4 times a day. Alternatively, Greyhound USA operates a bus from St Louis Bus Station to New Orleans Bus Station once daily. Tickets cost $110–220 and the journey takes 16h 50m.

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