There are 6 ways to get from St. Louis to Louisiana by plane, bus, train, bus (Greyhound), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Louis Armstrong New Orleans International Airport
best- Fly from Lambert–St. Louis International Airport (STL) to Louis Armstrong New Orleans International Airport (MSY)plane STL - MSY
3h 11m$472–852Fly to Lafayette Regional Airport
cheapest- Fly from Lambert–St. Louis International Airport (STL) to Lafayette Regional Airport (LFT)plane STL - LFT
5h 43m$108–506Bus, train
- Take the bus from St Louis Bus Station to Carbondale Intermodal Stationbus FlixBus N2521
- Take the train from Carbondale to New Orleans Union Passenger Terminaltrain City of New Orleans
16h 43m$355–572Bus (Greyhound)
- Take the bus from St Louis Bus Station to New Orleans Bus Stationbus Greyhound US1173
16h 50m$120–190Drive 676 mi
- Drive from St. Louis to New Orleanscar 676 mi
10h 58m$124–179Fly to Lake Charles Regional Airport
- Fly from Lambert–St. Louis International Airport (STL) to Lake Charles Regional Airport (LCH)plane STL - LCH
6h 20m$144–456
St. Louis to Louisiana by bus and train
Comparing Your Travel Options
The cheapest way to get from St. Louis to Louisiana is to bus which costs $120 - $190 and takes 16h 50m.
The fastest way to get from St. Louis to Louisiana is to fly which takes 3h 11m and costs $470 - $850.
Yes, there is a direct bus departing from St Louis Bus Station station and arriving at New Orleans Bus Station station. Services depart once daily, and operate every day. The journey takes approximately 16h 50m.
The distance between St. Louis and Louisiana is 623 miles. The road distance is 680 miles.
The best way to get from St. Louis to Louisiana without a car is to bus and train which takes 16h 43m and costs $350 - $600.
It takes approximately 3h 11m to get from St. Louis to Louisiana, including transfers.
St. Louis to Louisiana bus services, operated by Greyhound USA, depart from St Louis Bus Station.
The best way to get from St. Louis to Louisiana is to fly which takes 3h 11m and costs $470 - $850. Alternatively, you can bus, which costs $120 - $190 and takes 16h 50m.
St. Louis to Louisiana bus services, operated by Greyhound USA, arrive at New Orleans Bus Station.
Yes, the driving distance between St. Louis to Louisiana is 680 miles. It takes approximately 10h 58m to drive from St. Louis to Louisiana.
What companies run services between St. Louis, MO, USA and Louisiana, USA?
Southwest Airlines and Delta fly from Lambert–St. Louis International Airport (STL) to Louis Armstrong New Orleans International Airport (MSY) every 4 hours. Alternatively, Greyhound USA operates a bus from St Louis Bus Station to New Orleans Bus Station once daily. Tickets cost $120–190 and the journey takes 16h 50m.
- Website
- southwest.com
Flights from Lambert–St. Louis International Airport to Louis Armstrong New Orleans International Airport
- Ave. Duration
- 1h 43m
- When
- Every day
- Estimated price
- $100–600
Flights from Lambert–St. Louis International Airport to Louis Armstrong New Orleans International Airport via Nashville
- Ave. Duration
- 3h 43m
- When
- Tuesday to Friday
- Estimated price
- $110–650
Flights from Lambert–St. Louis International Airport to Louis Armstrong New Orleans International Airport via Dallas
- Ave. Duration
- 4h 7m
- When
- Tuesday to Friday
- Estimated price
- $130–700
Flights from Lambert–St. Louis International Airport to Louis Armstrong New Orleans International Airport via Houston Hobby Apt
- Ave. Duration
- 4h 7m
- When
- Monday, Thursday, and Friday
- Estimated price
- $130–700
- Website
- aa.com
Flights from Lambert–St. Louis International Airport to Lafayette Regional Airport via Dallas/Ft.Worth
- Ave. Duration
- 5h 15m
- When
- Every day
- Estimated price
- $95–500
Flights from Lambert–St. Louis International Airport to Lafayette Regional Airport via Charlotte
- Ave. Duration
- 5h 40m
- When
- Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $120–600
Flights from Lambert–St. Louis International Airport to Lake Charles Regional Airport via Dallas/Ft.Worth
- Ave. Duration
- 5h 33m
- When
- Monday, Tuesday, Thursday, Friday, Sunday, and Wednesday
- Estimated price
- $90–490
- Website
- united.com
Flights from Lambert–St. Louis International Airport to Lafayette Regional Airport via Houston
- Ave. Duration
- 4h 48m
- When
- Every day
- Estimated price
- $95–490
Flights from Lambert–St. Louis International Airport to Lake Charles Regional Airport via Houston
- Ave. Duration
- 6h 11m
- When
- Every day
- Estimated price
- $90–480
- Website
- delta.com
Flights from Lambert–St. Louis International Airport to Louis Armstrong New Orleans International Airport via Atlanta
- Ave. Duration
- 4h 5m
- When
- Every day
- Estimated price
- $120–700
Flights from Lambert–St. Louis International Airport to Lafayette Regional Airport via Atlanta
- Ave. Duration
- 4h 31m
- When
- Every day
- Estimated price
- $100–550
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Carbondale to New Orleans Union Passenger Terminal
- Ave. Duration
- 13h 53m
- Frequency
- Once daily
- Estimated price
- $340–550
- Website
- Amtrak
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from St Louis Bus Station to Carbondale Intermodal Station
- Ave. Duration
- 1h 50m
- Frequency
- 5 times a week
- Estimated price
- $15–23
- Schedules at
- Flixbus USA
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from St Louis Bus Station to Carbondale Intermodal Station
- Ave. Duration
- 2h
- Frequency
- Once daily
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from St Louis Bus Station to New Orleans Bus Station
- Ave. Duration
- 16h 50m
- Frequency
- Once daily
- Estimated price
- $120–190
- Website
- Greyhound
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Booking & Getting There
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