There are 6 ways to get from St. Louis to Lowell by plane, train (Amtrak), bus (Greyhound), car, bus, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Boston Logan Airport
best- Fly from Lambert–St. Louis International Airport (STL) to Boston Logan Airport (BOS)plane STL - BOS
5h 57m$474–920Fly to Theodore Francis Green State Airport, train
cheapest- Fly from Lambert–St. Louis International Airport (STL) to Theodore Francis Green State Airport (PVD)plane STL - PVD
- Take the train from TF Green Airport to Rugglestrain
- Take the train from North Station to Lowelltrain
9h 54m$94–422Train
- Take the train from St. Louis to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Bostontrain
- Take the train from North Station to Lowelltrain
29h 25m$712–1,151Bus
- Take the bus from St Louis Bus Station to Port Authority Bus Terminalbus
- Take the bus from New York to Bostonbus
- Take the bus from Boston to Robert B Kennedy Bus Transfer Centerbus
31h 57m$235–362Drive 1,152.6 mi
- Drive from St. Louis to Lowellcar 1,152.6 mi
20h 27m$211–304Fly to Manchester Airport, bus, train
- Fly from Lambert–St. Louis International Airport (STL) to Manchester Airport (MHT)plane STL - MHT
- Take the bus from Boston Manchester Airport to Bostonbus
- Take the train from North Station to Lowelltrain
9h 47m$118–580
St. Louis to Lowell by train and subway
Comparing Your Travel Options
The cheapest way to get from St. Louis to Lowell is to fly and train which costs $90 - $430 and takes 9h 54m.
The fastest way to get from St. Louis to Lowell is to fly which takes 5h 57m and costs $470 - $950.
No, there is no direct bus from St. Louis station to Lowell. However, there are services departing from St Louis Bus Station and arriving at Robert B Kennedy Bus Transfer Center via New York and Boston. The journey, including transfers, takes approximately 31h 57m.
No, there is no direct train from St. Louis to Lowell. However, there are services departing from St. Louis and arriving at Lowell via Chicago Union Station, Back Bay and North Station. The journey, including transfers, takes approximately 29h 25m.
The distance between St. Louis and Lowell is 1092 miles. The road distance is 1159.3 miles.
The best way to get from St. Louis to Lowell without a car is to train which takes 29h 25m and costs $700 - $1,200.
It takes approximately 5h 57m to get from St. Louis to Lowell, including transfers.
St. Louis to Lowell bus services, operated by Greyhound USA, depart from St Louis Bus Station.
St. Louis to Lowell train services, operated by Amtrak, depart from St. Louis station.
The best way to get from St. Louis to Lowell is to fly which takes 5h 57m and costs $470 - $950. Alternatively, you can train, which costs $700 - $1,200 and takes 29h 25m, you could also bus, which costs $230 - $370 and takes 31h 57m.
What companies run services between St. Louis, MO, USA and Lowell, MA, USA?
American Airlines and Southwest Airlines fly from Lambert–St. Louis International Airport (STL) to Boston Logan Airport (BOS) every 3 hours. Alternatively, you can take a train from St. Louis to Lowell via Chicago Union Station, Boston, Back Bay, North Station, and North Station in around 29h 25m.
- Website
- southwest.com
Flights from Lambert–St. Louis International Airport to Boston Logan Airport
- Ave. Duration
- 2h 34m
- When
- Every day
- Estimated price
- $110–600
Flights from Lambert–St. Louis International Airport to Boston Logan Airport via Chicago Midway
- Ave. Duration
- 4h 21m
- When
- Every day
- Estimated price
- $120–600
Flights from Lambert–St. Louis International Airport to Boston Logan Airport via Baltimore
- Ave. Duration
- 4h 27m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $120–600
Flights from Lambert–St. Louis International Airport to Manchester Airport via Chicago Midway
- Ave. Duration
- 5h 25m
- When
- Monday to Wednesday
- Estimated price
- $100–550
Flights from Lambert–St. Louis International Airport to Manchester Airport via Baltimore
- Ave. Duration
- 5h 40m
- When
- Every day
- Estimated price
- $110–550
Flights from Lambert–St. Louis International Airport to Manchester Airport via Nashville
- Ave. Duration
- 7h
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $110–550
Flights from Lambert–St. Louis International Airport to Theodore Francis Green State Airport via Baltimore
- Ave. Duration
- 5h 12m
- When
- Monday, Thursday, Friday, and Saturday
- Estimated price
- $80–390
Flights from Lambert–St. Louis International Airport to Theodore Francis Green State Airport via Chicago Midway
- Ave. Duration
- 4h 53m
- When
- Monday to Wednesday
- Estimated price
- $80–400
Flights from Lambert–St. Louis International Airport to Theodore Francis Green State Airport via Reagan Washington
- Ave. Duration
- 4h 32m
- When
- Saturday, Monday, and Sunday
- Estimated price
- $80–400
- Website
- aa.com
Flights from Lambert–St. Louis International Airport to Boston Logan Airport
- Ave. Duration
- 2h 41m
- When
- Every day
- Estimated price
- $110–600
Flights from Lambert–St. Louis International Airport to Manchester Airport via Reagan Washington
- Ave. Duration
- 6h 1m
- When
- Every day
- Estimated price
- $110–550
Flights from Lambert–St. Louis International Airport to Manchester Airport via Philadelphia
- Ave. Duration
- 5h 6m
- When
- Wednesday to Saturday
- Estimated price
- $110–550
Flights from Lambert–St. Louis International Airport to Theodore Francis Green State Airport via Philadelphia
- Ave. Duration
- 5h 5m
- When
- Every day
- Estimated price
- $75–390
Flights from Lambert–St. Louis International Airport to Theodore Francis Green State Airport via Reagan Washington
- Ave. Duration
- 5h 19m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $80–400
- Website
- delta.com
Flights from Lambert–St. Louis International Airport to Theodore Francis Green State Airport via Detroit
- Ave. Duration
- 4h 39m
- When
- Every day
- Estimated price
- $80–390
- Website
- united.com
Flights from Lambert–St. Louis International Airport to Manchester Airport via Washington Dulles
- Ave. Duration
- 5h 3m
- When
- Monday, Tuesday, Thursday, Friday, and Sunday
- Estimated price
- $110–550
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from St. Louis to Chicago Union Station
- Ave. Duration
- 4h 55m
- Frequency
- 5 times a day
- Estimated price
- $150–240
- Website
- Amtrak
Train from Chicago Union Station to Boston
- Ave. Duration
- 21h 54m
- Frequency
- Once daily
- Estimated price
- $550–900
- Website
- Amtrak
Train from North Station to Lowell
- Ave. Duration
- 47 min
- Frequency
- Hourly
- Estimated price
- $4–11
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $4–11
Train from North Station to Lowell
- Ave. Duration
- 47 min
- Frequency
- Hourly
- Estimated price
- $4–11
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $4–11
Train from TF Green Airport to Ruggles
- Ave. Duration
- 1h 22m
- Frequency
- Every 4 hours
- Estimated price
- $9–16
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $9–16
Train from North Station to Lowell
- Ave. Duration
- 47 min
- Frequency
- Hourly
- Estimated price
- $4–11
- Website
- Massachusetts Bay Transportation Authority
- Website
- MBTA: World Cup 2026
- Adult
- $4–11
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from St Louis Bus Station to Port Authority Bus Terminal
- Ave. Duration
- 24h 45m
- Frequency
- 3 times a day
- Estimated price
- $190–280
- Website
- Greyhound
Bus from Boston to Robert B Kennedy Bus Transfer Center
- Ave. Duration
- 45 min
- Frequency
- 5 times a week
- Estimated price
- $5–8
- Website
- Greyhound
Bus from Boston Manchester Airport to Boston
- Ave. Duration
- 1h 30m
- Frequency
- Twice daily
- Estimated price
- $9–14
- Website
- Greyhound
- Phone
- 1-800-343-9999
- Website
- Peter Pan
Bus from New York to Boston
- Ave. Duration
- 4h 35m
- Frequency
- Hourly
- Estimated price
- $40–75
- Website
- Peter Pan
Want to know more about travelling around United States
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Booking & Getting There
St. Louis to Lowell bus services, operated by Greyhound USA, arrive at Port Authority Bus Terminal station.
Lowell is 1h ahead of St. Louis. It is currently 11:28 AM in St. Louis and 12:28 PM in Lowell.
St. Louis to Lowell train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between St. Louis to Lowell is 1159 miles. It takes approximately 20h 27m to drive from St. Louis to Lowell.
Book your St. Louis to Lowell bus tickets online with Omio.
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