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How to get fromSt. Louis to Manchesterby plane, train, bus, bus (Greyhound), or car

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There are 5 ways to get from St. Louis to Manchester by plane, train, bus, bus (Greyhound), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Manchester Airport

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to Manchester Airport (MHT)plane plane STL - MHT
    6h 56m
    $104–554

  2. Train, bus

    1. Take the train from St. Louis to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Bostontrain train
    3. Take the bus from Boston to Manchester(Veterans Memorial Park)bus bus
    30h 7m
    $714–1,152

  3. Bus

    1. Take the bus from St Louis Bus Station to Port Authority Bus Terminalbus bus
    2. Take the bus from New York to Bostonbus bus
    3. Take the bus from Boston to Manchester(Veterans Memorial Park)bus bus
    32h 22m
    $242–374

  4. Drive  1,157.9 mi

    1. Drive from St. Louis to Manchestercar car 1,157.9 mi
    21h 9m
    $212–306

  5. Fly to Boston Logan Airport, bus

    1. Fly from Lambert–St. Louis International Airport (STL) to Boston Logan Airport (BOS)plane plane STL - BOS
    2. Take the bus from Boston to Manchester(Veterans Memorial Park)bus bus
    6h 37m
    $472–922

St. Louis to Manchester by train and bus

Calendar7Weekly Services
Duration30h 7mAverage Duration
Ticket$714Cheapest Price
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Comparing Your Travel Options

Map of how to get from St. Louis to Manchester.ExpandLaunch map view
  • Distance: 1,047.7 mi
  • Duration: 6h 56m

What companies run services between St. Louis, MO, USA and Manchester, NH, USA?

Southwest Airlines, American Airlines, and United Airlines fly from Lambert–St. Louis International Airport (STL) to Manchester Airport (MHT) every 4 hours. Alternatively, you can take a bus from St Louis Bus Station to Manchester(Veterans Memorial Park) via Port Authority Bus Terminal, New York, and Boston in around 32h 22m.

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