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How to get fromSt. Louis to Medinaby plane, bus (Greyhound), train (Amtrak), car, taxi, or bus (Flixbus)

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There are 6 ways to get from St. Louis to Medina by plane, bus (Greyhound), train (Amtrak), car, taxi, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Cleveland-Hopkins International Airport

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to Cleveland-Hopkins International Airport (CLE)plane plane STL - CLE
    3h 26m
    $552–982

  2. Drive 521.7 mi

    cheapest
    1. Drive from St. Louis to Medinacar car 521.7 mi
    8h 56m
    $96–138

  3. Bus

    1. Take the bus from St Louis Bus Station to Columbusbus bus Greyhound US0421
    2. Take the bus from Columbus to West Salem Bus Stationbus bus Greyhound US0105
    12h 39m
    $132–241

  4. Train (Amtrak)

    1. Take the train from St. Louis to Chicago Union Stationtrain train Lincoln Service / ...
    2. Take the train from Chicago Union Station to Cleveland Amtraktrain train Floridian / ...
    13h 23m
    $253–493

  5. Fly to Akron, taxi

    1. Fly from Lambert–St. Louis International Airport (STL) to Akron (CAK)plane plane STL - CAK
    2. Take the taxi from Akron-Airport-CAK to Medinataxi taxi
    6h 14m
    $158–472

  6. Bus via Chicago (Flixbus)

    1. Take the bus from St Louis Bus Station to Chicago Bus Stationbus bus FlixBus N2521 / ...
    2. Take the bus from Chicago Bus Station to Robert K Pfaff Transit Center - Akronbus bus FlixBus N2641
    16h
    $148–241

Lambert–St. Louis International Airport (STL) to Cleveland-Hopkins International Airport (CLE) flights

Calendar38Weekly Planes
Duration2h 38mAverage Duration
Ticket$108Cheapest Price
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Questions & Answers

Map of how to get from St. Louis to Medina.ExpandLaunch map view
  • Distance: 523 mi
  • Duration: 3h 26m

What companies run services between St. Louis, MO, USA and Medina, OH, USA?

Southwest Airlines and Delta fly from Lambert–St. Louis International Airport (STL) to Cleveland-Hopkins International Airport (CLE) 5 times a day. Alternatively, you can take a bus from St Louis Bus Station to Medina via Columbus and West Salem Bus Station in around 12h 39m.

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