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How to get fromSt. Louis to Middletonby train, bus, bus (Flixbus), car, or plane

Find Transport to Middleton

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There are 9 ways to get from St. Louis to Middleton by train, bus, bus (Flixbus), car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train, bus

    best
    1. Take the train from St. Louis to Chicago Union Stationtrain train Lincoln Service / ...
    2. Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus bus Van Galder
    10h 17m
    $118–240

  2. Drive 363.2 mi

    cheapest
    1. Drive from St. Louis to Middletoncar car 363.2 mi
    6h 9m
    $67–96

  3. Bus

    1. Take the bus from St Louis Bus Station to Chicago Bus Stationbus bus FlixBus 2510 / ...
    2. Take the bus from W Jackson Blvd, after S Clinton St to 250 N. Lake St - Madison UW Campusbus bus Van Galder
    11h 35m
    $78–140

  4. Fly Lambert–St. Louis International Airport to General Mitchell International Airport, bus

    1. Fly from Lambert–St. Louis International Airport (STL) to General Mitchell International Airport (MKE)plane plane STL - MKE
    2. Take the bus from Mitchell Airport to UW Madison Campus - N Lake Stbus bus
    6h 47m
    $498–878

  5. Train, bus via Milwaukee

    1. Take the train from St. Louis to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Milwaukeetrain train
    3. Take the bus from Milwaukee Intermodal to UW Madison Campus - N Lake Stbus bus
    10h 43m
    $132–264

  6. Fly Lambert–St. Louis International Airport to Dane County Regional Airport-Truax Field

    1. Fly from Lambert–St. Louis International Airport (STL) to Dane County Regional Airport-Truax Field (MSN)plane plane STL - MSN
    7h 53m
    $106–656

  7. Fly Lambert–St. Louis International Airport to Chicago O'Hare International Airport, bus

    1. Fly from Lambert–St. Louis International Airport (STL) to Chicago O'Hare International Airport (ORD)plane plane STL - ORD
    2. Take the bus from Multi-Modal/Rental Car Facility to 250 N. Lake St - Madison UW Campusbus bus
    7h 47m
    $298–810

  8. Train to Abraham Lincoln Capital Airport, fly to Chicago O'Hare International Airport, bus

    1. Take the train from St. Louis to Springfieldtrain train
    2. Fly from Abraham Lincoln Capital Airport (SPI) to Chicago O'Hare International Airport (ORD)plane plane SPI - ORD
    3. Take the bus from Multi-Modal/Rental Car Facility to 250 N. Lake St - Madison UW Campusbus bus
    8h 57m
    $100–406

  9. Bus to Decatur Airport, fly to Chicago O'Hare International Airport, bus

    1. Take the bus from St Louis Bus Station to Decatur Downtown Transportation Centerbus bus
    2. Fly from Decatur Airport (DEC) to Chicago O'Hare International Airport (ORD)plane plane DEC - ORD
    3. Take the bus from Multi-Modal/Rental Car Facility to 250 N. Lake St - Madison UW Campusbus bus
    9h 52m
    $92–380

St. Louis to Middleton by train and bus

Calendar38Weekly Services
Duration10h 17mAverage Duration
Ticket$118Cheapest Price
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Questions & Answers

Map of how to get from St. Louis to Middleton.ExpandLaunch map view
  • Distance: 442.2 mi
  • Duration: 10h 17m

What companies run services between St. Louis, MO, USA and Middleton, WI, USA?

You can take a bus from St Louis Bus Station to Parmenter at Franklin via Chicago Bus Station, W Jackson Blvd, after S Clinton St, 250 N. Lake St - Madison UW Campus, and East Campus in around 11h 35m. Alternatively, United Airlines, Delta, and American Airlines fly from Lambert–St. Louis International Airport (STL) to Dane County Regional Airport-Truax Field (MSN) hourly.

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