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How to get fromSt. Louis to Middletownby plane, train, bus, car, or subway

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There are 11 ways to get from St. Louis to Middletown by plane, train, bus, car, or subway

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Philadelphia International Airport, train, bus

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to Philadelphia International Airport (PHL)plane plane STL - PHL
    2. Take the train from 30th Street Station to Wilmingtontrain train
    3. Take the bus from 11Th St @ King St to Odessa Park & Ridebus bus
    7h 27m
    $164–1,364

  2. Fly to Baltimore-Washington International Airport, train, bus

    cheapest
    1. Fly from Lambert–St. Louis International Airport (STL) to Baltimore-Washington International Airport (BWI)plane plane STL - BWI
    2. Take the train from BWI Thurgood Marshall to Wilmingtontrain train
    3. Take the bus from 11Th St @ King St to Odessa Park & Ridebus bus
    8h 39m
    $144–1,262

  3. Bus, train

    1. Take the bus from St Louis Bus Station to Philadelphia Bus Stationbus bus
    2. Take the train from Jefferson Station to Wilmingtontrain train Wil
    3. Take the bus from Newark Transit Hub to Main St @ N Catherine St Wbbus bus 046
    26h 51m
    $145–270

  4. Bus, train via Indianapolis

    1. Take the bus from St Louis Bus Station to Indianapolis Union Stationbus bus
    2. Take the train from Indianapolis to Wilmingtontrain train
    3. Take the bus from 11Th St @ King St to Odessa Park & Ridebus bus 301
    28h 4m
    $301–627

  5. Drive 872.8 mi

    1. Drive from St. Louis to Middletowncar car 872.8 mi
    15h 24m
    $160–231

  6. Fly to Ronald Reagan Washington National Airport, train, bus

    1. Fly from Lambert–St. Louis International Airport (STL) to Ronald Reagan Washington National Airport (DCA)plane plane STL - DCA
    2. Take the train from Washington Union Station to Newark Amtraktrain train
    3. Take the bus from Newark Transit Hub to Main St @ N Catherine St Wbbus bus
    8h 57m
    $200–460

  7. Fly to Newark Liberty International Airport, train, bus

    1. Fly from Lambert–St. Louis International Airport (STL) to Newark Liberty International Airport (EWR)plane plane STL - EWR
    2. Take the train from Newark Liberty International Airport to Wilmingtontrain train
    3. Take the bus from 11Th St @ King St to Odessa Park & Ridebus bus
    9h 11m
    $406–880

  8. Fly to Washington Dulles International Airport, subway, train, bus

    1. Fly from Lambert–St. Louis International Airport (STL) to Washington Dulles International Airport (IAD)plane plane STL - IAD
    2. Take the subway from Washington Dulles International Airport, Silver Line Center Platform to New Carrollton, Orange Line Center Platformsubway subway
    3. Take the train from New Carrollton Amtrak Station to Newark Amtraktrain train
    4. Take the bus from Newark Transit Hub to Main St @ N Catherine St Wbbus bus
    10h 10m
    $216–1,072

  9. Fly to Laguardia Airport, train, bus

    1. Fly from Lambert–St. Louis International Airport (STL) to Laguardia Airport (LGA)plane plane STL - LGA
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Wilmingtontrain train
    3. Take the bus from 11Th St @ King St to Odessa Park & Ridebus bus
    10h 12m
    $176–1,106

  10. Train, bus via Washington

    1. Take the train from St. Louis to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Washington Union Stationtrain train
    3. Take the train from Washington Union Station to Wilmingtontrain train
    4. Take the bus from 11Th St @ King St to Odessa Park & Ridebus bus 301
    28h 23m
    $358–1,393

  11. Train, bus

    1. Take the train from St. Louis to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Wilmingtontrain train
    3. Take the bus from Newark Transit Hub to Main St @ N Catherine St Wbbus bus 046
    34h 18m
    $414–892

St. Louis to Middletown by bus and train

Calendar40Weekly Services
Duration26h 51mAverage Duration
Ticket$145Cheapest Price
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Questions & Answers

Map of how to get from St. Louis to Middletown.ExpandLaunch map view
  • Distance: 888 mi
  • Duration: 7h 27m

What companies run services between St. Louis, MO, USA and Middletown, DE, USA?

There is no direct connection from St. Louis to Middletown. However, you can take the train to LAMBERT AIRPORT TERMINAL #1 station, walk to Lambert–St. Louis International Airport (STL) airport, fly to Philadelphia International Airport (PHL), walk to Airport Terminal A, take the train to Gray 30th St Station, take the train to Wilmington, walk to Wilmington Tc, take the line 006 bus to 10Th St @ King St, walk to 11Th St @ King St, take the bus to Odessa Park & Ride, then take the line 046 bus to Main St @ N Catherine St Eb. Alternatively, you can take a bus from St Louis Bus Station to Main St @ N Catherine St Wb via Philadelphia Bus Station, Jefferson Station, Wilmington, Wilmington Tc, and Newark Transit Hub in around 26h 51m.

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