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How to get fromSt. Louis to Mission Viejoby plane, bus (Greyhound, Amtrak), train (Amtrak), car, or train

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There are 6 ways to get from St. Louis to Mission Viejo by plane, bus (Greyhound, Amtrak), train (Amtrak), car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to John Wayne Airport Orange County

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to John Wayne Airport Orange County (SNA)plane plane STL - SNA
    7h 12m
    $268–958

  2. Fly to San Diego International Airport, train

    cheapest
    1. Fly from Lambert–St. Louis International Airport (STL) to San Diego International Airport (SAN)plane plane STL - SAN
    2. Take the train from San Diego to San Juan Capistrano Amtrak Stationtrain train
    9h 12m
    $158–250

  3. Bus

    1. Take the bus from St Louis Bus Station to Los Angeles Union Stationbus bus Greyhound US1210
    2. Take the bus from Los Angeles to San Juan Capistrano Amtrak Stationbus bus Amtrak Thruway Connecting Service
    42h 27m
    $325–603

  4. Train via Kansas City (Amtrak)

    1. Take the train from St. Louis to Kansas Citytrain train Missouri River Runner / ...
    2. Take the train from Kansas City to Fullerton Amtrak Stationtrain train Southwest Chief
    43h 57m
    $650–1,394

  5. Drive 1,818.3 mi

    1. Drive from St. Louis to Mission Viejocar car 1,818.3 mi
    28h 39m
    $332–480

  6. Train (Amtrak)

    1. Take the train from St. Louis to Los Angelestrain train Texas Eagle
    2. Take the train from Los Angeles to San Juan Capistrano Amtrak Stationtrain train Pacific Surfliner
    2d 14h
    $813–1,629

St. Louis to Mission Viejo by bus and foot

Calendar7Weekly Services
Duration42h 27mAverage Duration
Ticket$325Cheapest Price
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Questions & Answers

Map of how to get from St. Louis to Mission Viejo.ExpandLaunch map view
  • Distance: 1,593.5 mi
  • Duration: 7h 12m

What companies run services between St. Louis, MO, USA and Mission Viejo, CA, USA?

Southwest Airlines, United Airlines, and two other airlines fly from Lambert–St. Louis International Airport (STL) to John Wayne Airport Orange County (SNA) hourly. Alternatively, you can take a bus from St Louis Bus Station to Cabot-La Paz via Los Angeles Union Station, Los Angeles, San Juan Capistrano Amtrak Station, and Camino Capistrano-Old Mission in around 42h 27m.

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