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How to get fromSt. Louis to Mississippiby plane, bus (Greyhound), bus, train, or car

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There are 4 ways to get from St. Louis to Mississippi by plane, bus (Greyhound), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to Memphis (MEM)plane plane STL - MEM
    4h 47m
    $154–780

  2. Bus (Greyhound)

    cheapest
    1. Take the bus from St Louis Bus Station to Jacksonbus bus Greyhound US1173
    11h 45m
    $80–160

  3. Bus, train

    1. Take the bus from St. Louis to Carbondalebus bus Amtrak Thruway Connecting Service
    2. Take the train from Carbondale to Jacksontrain train City of New Orleans
    12h 46m
    $155–336

  4. Drive 490.4 mi

    1. Drive from St. Louis to Jacksoncar car 490.4 mi
    7h 55m
    $90–130

St. Louis to Mississippi by bus (Greyhound)

Calendar7Weekly Buses
Duration11h 45mAverage Duration
Ticket$80Cheapest Price
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Questions & Answers

Map of how to get from St. Louis to Mississippi.ExpandLaunch map view
  • Distance: 277.4 mi
  • Duration: 4h 47m

What companies run services between St. Louis, MO, USA and Mississippi, USA?

Southwest Airlines, Delta, and two other airlines fly from Lambert–St. Louis International Airport (STL) to Memphis (MEM) hourly. Alternatively, Greyhound USA operates a bus from St Louis Bus Station to Jackson once daily. Tickets cost $80–160 and the journey takes 11h 45m.

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Need to know: Greyhound

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