There are 3 ways to get from St. Louis to Murrells Inlet by plane, bus (Flixbus, Greyhound), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Lambert–St. Louis International Airport (STL) to Myrtle Beach (MYR)plane STL - MYR
3h 42m$118–472Bus
- Take the bus from St Louis Bus Station to Atlanta Bus Stationbus FlixBus N2521
- Take the bus from Atlanta Bus Station to Myrtle Beach Bus Stationbus Greyhound US0641S
20h 11m$193–300Drive 889.2 mi
- Drive from St. Louis to Murrells Inletcar 889.2 mi
15h 44m$163–235
Lambert–St. Louis International Airport (STL) to Myrtle Beach (MYR) flights
Comparing Your Travel Options
The cheapest way to get from St. Louis to Murrells Inlet is to drive which costs $160 - $240 and takes 15h 44m.
The fastest way to get from St. Louis to Murrells Inlet is to fly which takes 3h 42m and costs $110 - $480.
No, there is no direct bus from St. Louis station to Murrells Inlet station. However, there are services departing from St Louis Bus Station and arriving at Myrtle Beach Bus Station via Atlanta Bus Station. The journey, including transfers, takes approximately 20h 11m.
The distance between St. Louis and Murrells Inlet is 758 miles. The road distance is 894.4 miles.
The best way to get from St. Louis to Murrells Inlet without a car is to bus which takes 20h 11m and costs $190 - $300.
It takes approximately 3h 42m to get from St. Louis to Murrells Inlet, including transfers.
St. Louis to Murrells Inlet bus services, operated by Flixbus USA, depart from St Louis Bus Station.
The best way to get from St. Louis to Murrells Inlet is to fly which takes 3h 42m and costs $110 - $480. Alternatively, you can bus, which costs $190 - $300 and takes 20h 11m.
St. Louis to Murrells Inlet bus services, operated by Flixbus USA, arrive at Atlanta Bus Station.
Murrells Inlet is 1h ahead of St. Louis. It is currently 2:45 PM in St. Louis and 3:45 PM in Murrells Inlet.
What companies run services between St. Louis, MO, USA and Murrells Inlet, SC, USA?
Southwest Airlines and American Airlines fly from Lambert–St. Louis International Airport (STL) to Myrtle Beach (MYR) 5 times a day. Alternatively, you can take a bus from St Louis Bus Station to Murrells Inlet via Atlanta Bus Station and Myrtle Beach Bus Station in around 20h 11m.
- Website
- southwest.com
Flights from Lambert–St. Louis International Airport to Myrtle Beach
- Ave. Duration
- 1h 50m
- When
- Saturday
- Estimated price
- $75–420
Flights from Lambert–St. Louis International Airport to Myrtle Beach via Nashville
- Ave. Duration
- 4h 1m
- When
- Every day
- Estimated price
- $75–420
Flights from Lambert–St. Louis International Airport to Myrtle Beach via Chicago Midway
- Ave. Duration
- 4h 15m
- When
- Monday, Thursday, and Friday
- Estimated price
- $90–470
Flights from Lambert–St. Louis International Airport to Myrtle Beach via Pittsburgh
- Ave. Duration
- 4h 20m
- When
- Saturday
- Estimated price
- $95–480
- Website
- aa.com
Flights from Lambert–St. Louis International Airport to Myrtle Beach via Charlotte
- Ave. Duration
- 4h
- When
- Every day
- Estimated price
- $75–420
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from St Louis Bus Station to Atlanta Bus Station
- Ave. Duration
- 10h 10m
- Frequency
- 5 times a week
- Estimated price
- $85–130
- Schedules at
- Flixbus USA
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from St Louis Bus Station to Atlanta Bus Station
- Ave. Duration
- 11h 40m
- Frequency
- Once daily
- Estimated price
- $95–150
- Website
- Greyhound
Bus from Atlanta Bus Station to Myrtle Beach Bus Station
- Ave. Duration
- 8h 40m
- Frequency
- Once daily
- Estimated price
- $65–100
- Website
- Greyhound
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Booking & Getting There
Yes, the driving distance between St. Louis to Murrells Inlet is 894 miles. It takes approximately 15h 44m to drive from St. Louis to Murrells Inlet.
There are 3132+ hotels available in Murrells Inlet.