There are 6 ways to get from St. Louis to Muscle Shoals by plane, taxi, bus (Amtrak, Flixbus, Greyhound), car, or bus (Greyhound, Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Huntsville International Airport-Carl T Jones Field, taxi
best- Fly from Lambert–St. Louis International Airport (STL) to Huntsville International Airport-Carl T Jones Field (HSV)plane STL - HSV
- Take the taxi from Huntsville International Airport-Carl T Jones Field (HSV) to Muscle Shoalstaxi
5h 54m$252–862Drive 353.3 mi
cheapest- Drive from St. Louis to Muscle Shoalscar 353.3 mi
7h 13m$65–94Bus via Carbondale
- Take the bus from St. Louis to Carbondalebus
- Take the bus from Carbondale Intermodal Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Florencebus
19h 47m$147–235Fly to Nashville, drive
- Fly from Lambert–St. Louis International Airport (STL) to Nashville (BNA)plane STL - BNA
- Drive from Nashville-Airport-BNA to Muscle Shoalscar
5h 31m$164–788Fly to Birmingham–Shuttlesworth International Airport, drive
- Fly from Lambert–St. Louis International Airport (STL) to Birmingham–Shuttlesworth International Airport (BHM)plane STL - BHM
- Drive from Birmingham-Airport-BHM to Muscle Shoalscar
6h 34m$152–832Bus
- Take the bus from St Louis Bus Station to Atlanta Bus Stationbus Greyhound US0186
- Take the bus from Atlanta Bus Station to Florencebus Greyhound US0622s
20h 22m$151–241
Lambert–St. Louis International Airport (STL) to Huntsville International Airport-Carl T Jones Field (HSV) flights
Comparing Your Travel Options
The cheapest way to get from St. Louis to Muscle Shoals is to drive which costs $60 - $95 and takes 7h 13m.
The fastest way to get from St. Louis to Muscle Shoals is to fly and drive which takes 5h 31m and costs $160 - $800.
No, there is no direct bus from St. Louis to Muscle Shoals. However, there are services departing from St. Louis and arriving at Florence via Carbondale Intermodal Station and Atlanta Bus Station. The journey, including transfers, takes approximately 19h 47m.
The distance between St. Louis and Muscle Shoals is 420 miles. The road distance is 355.4 miles.
The best way to get from St. Louis to Muscle Shoals without a car is to bus via Carbondale which takes 19h 47m and costs $140 - $240.
It takes approximately 5h 54m to get from St. Louis to Muscle Shoals, including transfers.
St. Louis to Muscle Shoals bus services, operated by Amtrak, depart from St. Louis station.
St. Louis to Muscle Shoals bus services, operated by Amtrak, arrive at Carbondale station.
Yes, the driving distance between St. Louis to Muscle Shoals is 355 miles. It takes approximately 7h 13m to drive from St. Louis to Muscle Shoals.
Book your St. Louis to Muscle Shoals bus tickets online with Omio.
What companies run services between St. Louis, MO, USA and Muscle Shoals, AL, USA?
You can take a bus from St. Louis to Muscle Shoals via Carbondale Intermodal Station, Atlanta Bus Station, and Florence in around 19h 47m.
- Website
- southwest.com
Flights from Lambert–St. Louis International Airport to Nashville
- Ave. Duration
- 1h 10m
- When
- Every day
- Estimated price
- $60–410
Flights from Lambert–St. Louis International Airport to Birmingham–Shuttlesworth International Airport via Nashville
- Ave. Duration
- 3h 35m
- When
- Saturday to Wednesday
- Estimated price
- $130–800
Flights from Lambert–St. Louis International Airport to Birmingham–Shuttlesworth International Airport via Chicago Midway
- Ave. Duration
- 4h 11m
- When
- Sunday, Tuesday, Wednesday, Monday, Thursday, and Friday
- Estimated price
- $180–1,000
Flights from Lambert–St. Louis International Airport to Birmingham–Shuttlesworth International Airport via Dallas
- Ave. Duration
- 4h 47m
- When
- Sunday, Tuesday, Wednesday, Monday, Thursday, and Friday
- Estimated price
- $230–1,200
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from St. Louis to Carbondale
- Ave. Duration
- 2h
- Frequency
- Once daily
- Estimated price
- $22–35
- Website
- Amtrak
- Ave. Duration
- 1h 6m
- Estimated price
- $130–160
AAAA Cab Co.
- Phone
- +1 256-288-0909
A Metro Cab Co.
- Phone
- +1 256-534-5000
- Website
- facebook.com
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Booking & Getting There
There are 49+ hotels available in Muscle Shoals.





