There are 5 ways to get from St. Louis to Muscle Shoals by plane, taxi, bus (Flixbus, Greyhound), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Huntsville International Airport-Carl T Jones Field, taxi
best- Fly from Lambert–St. Louis International Airport (STL) to Huntsville International Airport-Carl T Jones Field (HSV)plane STL - HSV
- Take the taxi from Huntsville International Airport-Carl T Jones Field (HSV) to Muscle Shoalstaxi
5h 59m$252–862Drive 353.3 mi
cheapest- Drive from St. Louis to Muscle Shoalscar 353.3 mi
7h 13m$65–94Bus
- Take the bus from St Louis Bus Station to Atlanta Bus Stationbus FlixBus N2521
- Take the bus from Atlanta Bus Station to Florencebus Greyhound US0622s
18h 52m$165–259Fly to Birmingham–Shuttlesworth International Airport, drive
- Fly from Lambert–St. Louis International Airport (STL) to Birmingham–Shuttlesworth International Airport (BHM)plane STL - BHM
- Drive from Birmingham-Airport-BHM to Muscle Shoalscar
7h 14m$162–932Fly to Nashville, drive
- Fly from Lambert–St. Louis International Airport (STL) to Nashville (BNA)plane STL - BNA
- Drive from Nashville-Airport-BNA to Muscle Shoalscar
5h 31m$154–738
Lambert–St. Louis International Airport (STL) to Huntsville International Airport-Carl T Jones Field (HSV) flights
Comparing Your Travel Options
The cheapest way to get from St. Louis to Muscle Shoals is to drive which costs $60 - $95 and takes 7h 13m.
The fastest way to get from St. Louis to Muscle Shoals is to fly and drive which takes 5h 31m and costs $150 - $750.
No, there is no direct bus from St. Louis station to Muscle Shoals. However, there are services departing from St Louis Bus Station and arriving at Florence via Atlanta Bus Station. The journey, including transfers, takes approximately 18h 52m.
The distance between St. Louis and Muscle Shoals is 420 miles. The road distance is 355.4 miles.
The best way to get from St. Louis to Muscle Shoals without a car is to bus which takes 18h 52m and costs $160 - $260.
It takes approximately 5h 59m to get from St. Louis to Muscle Shoals, including transfers.
St. Louis to Muscle Shoals bus services, operated by Flixbus USA, depart from St Louis Bus Station.
St. Louis to Muscle Shoals bus services, operated by Flixbus USA, arrive at Atlanta Bus Station.
Yes, the driving distance between St. Louis to Muscle Shoals is 355 miles. It takes approximately 7h 13m to drive from St. Louis to Muscle Shoals.
Book your St. Louis to Muscle Shoals bus tickets online with Omio.
What companies run services between St. Louis, MO, USA and Muscle Shoals, AL, USA?
You can take a bus from St Louis Bus Station to Muscle Shoals via Atlanta Bus Station and Florence in around 18h 52m.
- Website
- aa.com
Flights from Lambert–St. Louis International Airport to Huntsville International Airport-Carl T Jones Field via Charlotte
- Ave. Duration
- 5h 10m
- When
- Every day
- Estimated price
- $150–800
Flights from Lambert–St. Louis International Airport to Huntsville International Airport-Carl T Jones Field via Dallas/Ft.Worth
- Ave. Duration
- 5h 28m
- When
- Every day
- Estimated price
- $170–850
Flights from Lambert–St. Louis International Airport to Huntsville International Airport-Carl T Jones Field via Chicago O'Hare
- Ave. Duration
- 5h 8m
- When
- Every day
- Estimated price
- $130–750
Flights from Lambert–St. Louis International Airport to Huntsville International Airport-Carl T Jones Field via Reagan Washington
- Ave. Duration
- 6h 20m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $190–900
Flights from Lambert–St. Louis International Airport to Birmingham–Shuttlesworth International Airport via Charlotte
- Ave. Duration
- 4h 49m
- When
- Every day
- Estimated price
- $210–1,100
Flights from Lambert–St. Louis International Airport to Birmingham–Shuttlesworth International Airport via Chicago O'Hare
- Ave. Duration
- 4h 53m
- When
- Saturday
- Estimated price
- $200–1,100
- Website
- southwest.com
Flights from Lambert–St. Louis International Airport to Birmingham–Shuttlesworth International Airport via Nashville
- Ave. Duration
- 4h 37m
- When
- Every day
- Estimated price
- $140–900
Flights from Lambert–St. Louis International Airport to Birmingham–Shuttlesworth International Airport via Dallas
- Ave. Duration
- 5h 5m
- When
- Tuesday, Saturday, and Wednesday
- Estimated price
- $240–1,200
Flights from Lambert–St. Louis International Airport to Birmingham–Shuttlesworth International Airport via Chicago Midway
- Ave. Duration
- 5h 55m
- When
- Tuesday, Wednesday, Monday, Thursday, Friday, and Sunday
- Estimated price
- $200–1,100
Flights from Lambert–St. Louis International Airport to Nashville
- Ave. Duration
- 1h 12m
- When
- Every day
- Estimated price
- $60–410
- Website
- delta.com
Flights from Lambert–St. Louis International Airport to Huntsville International Airport-Carl T Jones Field via Atlanta
- Ave. Duration
- 4h 20m
- When
- Every day
- Estimated price
- $120–700
Flights from Lambert–St. Louis International Airport to Birmingham–Shuttlesworth International Airport via Atlanta
- Ave. Duration
- 4h 53m
- When
- Every day
- Estimated price
- $170–950
- Website
- united.com
Flights from Lambert–St. Louis International Airport to Huntsville International Airport-Carl T Jones Field via Chicago O'Hare
- Ave. Duration
- 5h 26m
- When
- Every day
- Estimated price
- $130–750
Flights from Lambert–St. Louis International Airport to Birmingham–Shuttlesworth International Airport via Chicago O'Hare
- Ave. Duration
- 4h 42m
- When
- Every day
- Estimated price
- $200–1,100
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from St Louis Bus Station to Atlanta Bus Station
- Ave. Duration
- 10h 10m
- Frequency
- 5 times a week
- Estimated price
- $85–130
- Schedules at
- Flixbus USA
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from St Louis Bus Station to Atlanta Bus Station
- Ave. Duration
- 11h 40m
- Frequency
- Once daily
- Estimated price
- $95–150
- Website
- Greyhound
Bus from Atlanta Bus Station to Florence
- Ave. Duration
- 7h 30m
- Frequency
- Once daily
- Estimated price
- $55–85
- Website
- Greyhound
- Ave. Duration
- 1h 6m
- Estimated price
- $130–160
AAAA Cab Co.
- Phone
- +1 256-288-0909
A Metro Cab Co.
- Phone
- +1 256-534-5000
- Website
- facebook.com
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Booking & Getting There
There are 48+ hotels available in Muscle Shoals.



