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How to get fromSt. Louis to Museum of Science and Industryby train (Amtrak), bus (Flixbus), car, plane, or train

Find Transport to Museum of Science and Industry

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There are 6 ways to get from St. Louis to Museum of Science and Industry by train (Amtrak), bus (Flixbus), car, plane, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train (Amtrak)

    best
    1. Take the train from St. Louis to Chicago Union Stationtrain train Lincoln Service / ...
    5h 41m
    $92–189

  2. Bus (Flixbus)

    cheapest
    1. Take the bus from St Louis Bus Station to Chicagobus bus FlixBus N2521
    6h 54m
    $48–78

  3. Drive 292.7 mi

    1. Drive from St. Louis to Museum of Science and Industrycar car 292.7 mi
    5h 7m
    $54–78

  4. Fly Lambert–St. Louis International Airport to Chicago Midway International Airport, train

    1. Fly from Lambert–St. Louis International Airport (STL) to Chicago Midway International Airport (MDW)plane plane STL - MDW
    2. Take the train from Museum Campus/11th St. to 55th - 56th - 57th St.train train
    3h 50m
    $58–382

  5. Fly Lambert–St. Louis International Airport to Chicago O'Hare International Airport, train

    1. Fly from Lambert–St. Louis International Airport (STL) to Chicago O'Hare International Airport (ORD)plane plane STL - ORD
    2. Take the train from Van Buren St. to 55th - 56th - 57th St.train train
    4h 21m
    $318–712

  6. Train to Abraham Lincoln Capital Airport, fly to Chicago O'Hare International Airport

    1. Take the train from St. Louis to Springfieldtrain train
    2. Fly from Abraham Lincoln Capital Airport (SPI) to Chicago O'Hare International Airport (ORD)plane plane SPI - ORD
    5h 31m
    $77–328

St. Louis to Museum of Science and Industry by train, bus, and foot (Amtrak)

Calendar38Weekly Services
Duration5h 41mAverage Duration
Ticket$92Cheapest Price
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Questions & Answers

Map of how to get from St. Louis to Museum of Science and Industry.ExpandLaunch map view
  • Distance: 288.5 mi
  • Duration: 5h 41m

What companies run services between St. Louis, MO, USA and Museum of Science and Industry, IL, USA?

Amtrak operates a train from St. Louis to Chicago Union Station 5 times a day. Tickets cost $85–190 and the journey takes 4h 55m. Alternatively, Flixbus USA operates a bus from St Louis Bus Station to Chicago 5 times a week. Tickets cost $45–80 and the journey takes 5h 40m.

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