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How to get fromSt. Louis to Myrtle Beachby plane, bus (Amtrak, Flixbus, Greyhound), car, or bus (Greyhound, Flixbus)

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There are 4 ways to get from St. Louis to Myrtle Beach by plane, bus (Amtrak, Flixbus, Greyhound), car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to Myrtle Beach (MYR)plane plane STL - MYR
    3h 32m
    $98–456

  2. Bus via Carbondale

    1. Take the bus from St. Louis to Carbondalebus bus
    2. Take the bus from Carbondale Intermodal Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Myrtle Beach Bus Stationbus bus
    20h 45m
    $135–278

  3. Drive 881.1 mi

    1. Drive from St. Louis to Myrtle Beachcar car 881.1 mi
    15h 31m
    $161–233

  4. Bus

    1. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus Greyhound US0186
    2. Take the bus from Atlanta Bus Station to Myrtle Beach Bus Stationbus bus Greyhound US0641S
    21h 20m
    $142–272

St. Louis to Myrtle Beach by bus

Calendar5Weekly Buses
Duration20h 45mAverage Duration
Ticket$135Cheapest Price
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Questions & Answers

Map of how to get from St. Louis to Myrtle Beach.ExpandLaunch map view
  • Distance: 743.3 mi
  • Duration: 3h 32m

What companies run services between St. Louis, MO, USA and Myrtle Beach, SC, USA?

Southwest Airlines, Delta, and American Airlines fly from Lambert–St. Louis International Airport (STL) to Myrtle Beach (MYR) 5 times a day. Alternatively, you can take a bus from St. Louis to Myrtle Beach Bus Station via Carbondale Intermodal Station and Atlanta Bus Station in around 20h 45m.

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