There are 3 ways to get from St. Louis to Myrtle Beach by plane, bus (Flixbus, Greyhound), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Lambert–St. Louis International Airport (STL) to Myrtle Beach (MYR)plane STL - MYR
3h 27m$88–436Bus
- Take the bus from St Louis Bus Station to Atlanta Bus Stationbus FlixBus N2521
- Take the bus from Atlanta Bus Station to Myrtle Beach Bus Stationbus Greyhound US0641S
19h 50m$152–246Drive 881.1 mi
- Drive from St. Louis to Myrtle Beachcar 881.1 mi
15h 31m$161–233
St. Louis to Myrtle Beach by bus
Comparing Your Travel Options
The cheapest way to get from St. Louis to Myrtle Beach is to drive which costs $160 - $240 and takes 15h 31m.
The fastest way to get from St. Louis to Myrtle Beach is to fly which takes 3h 27m and costs $85 - $440.
No, there is no direct bus from St. Louis station to Myrtle Beach station. However, there are services departing from St Louis Bus Station and arriving at Myrtle Beach Bus Station via Atlanta Bus Station. The journey, including transfers, takes approximately 19h 50m.
The distance between St. Louis and Myrtle Beach is 748 miles. The road distance is 886.3 miles.
The best way to get from St. Louis to Myrtle Beach without a car is to bus which takes 19h 50m and costs $150 - $250.
It takes approximately 3h 27m to get from St. Louis to Myrtle Beach, including transfers.
St. Louis to Myrtle Beach bus services, operated by Flixbus USA, depart from St Louis Bus Station.
The best way to get from St. Louis to Myrtle Beach is to fly which takes 3h 27m and costs $85 - $440. Alternatively, you can bus, which costs $150 - $250 and takes 19h 50m.
St. Louis to Myrtle Beach bus services, operated by Flixbus USA, arrive at Atlanta Bus Station.
Myrtle Beach is 1h ahead of St. Louis. It is currently 1:53 PM in St. Louis and 2:53 PM in Myrtle Beach.
What companies run services between St. Louis, MO, USA and Myrtle Beach, SC, USA?
Southwest Airlines and American Airlines fly from Lambert–St. Louis International Airport (STL) to Myrtle Beach (MYR) 5 times a day. Alternatively, you can take a bus from St Louis Bus Station to Myrtle Beach Bus Station via Atlanta Bus Station in around 19h 50m.
- Website
- southwest.com
Flights from Lambert–St. Louis International Airport to Myrtle Beach
- Ave. Duration
- 1h 50m
- When
- Saturday
- Estimated price
- $75–420
Flights from Lambert–St. Louis International Airport to Myrtle Beach via Nashville
- Ave. Duration
- 4h 15m
- When
- Monday, Thursday, Friday, and Saturday
- Estimated price
- $75–420
Flights from Lambert–St. Louis International Airport to Myrtle Beach via Chicago Midway
- Ave. Duration
- 4h 15m
- When
- Monday, Thursday, and Friday
- Estimated price
- $90–470
Flights from Lambert–St. Louis International Airport to Myrtle Beach via Pittsburgh
- Ave. Duration
- 4h 20m
- When
- Saturday
- Estimated price
- $95–480
- Website
- aa.com
Flights from Lambert–St. Louis International Airport to Myrtle Beach via Charlotte
- Ave. Duration
- 4h 16m
- When
- Every day
- Estimated price
- $75–420
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from St Louis Bus Station to Atlanta Bus Station
- Ave. Duration
- 10h 10m
- Frequency
- 5 times a week
- Estimated price
- $85–130
- Schedules at
- Flixbus USA
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from St Louis Bus Station to Atlanta Bus Station
- Ave. Duration
- 11h 40m
- Frequency
- Once daily
- Estimated price
- $95–150
- Website
- Greyhound
Bus from Atlanta Bus Station to Myrtle Beach Bus Station
- Ave. Duration
- 8h 40m
- Frequency
- Once daily
- Estimated price
- $65–100
- Website
- Greyhound
Want to know more about travelling around United States
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Booking & Getting There
Yes, the driving distance between St. Louis to Myrtle Beach is 886 miles. It takes approximately 15h 31m to drive from St. Louis to Myrtle Beach.
Book your St. Louis to Myrtle Beach bus tickets online with Omio and FlixBus.
There are 5610+ hotels available in Myrtle Beach.



