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How to get fromSt. Louis to New Madridby bus, taxi, train, or car

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There are 3 ways to get from St. Louis to New Madrid by bus, taxi, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, taxi

    best
    1. Take the bus from St Louis Bus Station to Cape Girardeaubus bus Greyhound US1173
    2. Take the taxi from Cape Girardeau to New Madridtaxi taxi
    2h 58m
    $176–230
  2. Drive 163.8 mi

    cheapest
    1. Drive from St. Louis to New Madridcar car 163.8 mi
    2h 44m
    $30–44
  3. Train, drive (Amtrak)

    1. Take the train from St. Louis to Poplar Bluff Stationtrain train Texas Eagle
    2. Drive from Poplar Bluff Station to New Madridcar car
    5h 14m
    $63–122

Questions & Answers

What companies run services between St. Louis, MO, USA and New Madrid, MO, USA?

There is no direct connection from St. Louis to New Madrid. However, you can take the bus to Cape Girardeau then take the taxi to New Madrid. Alternatively, you can take a train from St. Louis to New Madrid via Poplar Bluff Station in around 5h 14m.

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