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How to get fromSt. Louis to Nicholasvilleby bus, car, or plane

Find Transport to Nicholasville

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There are 7 ways to get from St. Louis to Nicholasville by bus, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, drive via Louisville

    best
    1. Take the bus from St Louis Bus Station to Evansville Bus Stationbus bus
    2. Take the bus from Evansville, IN to Louisville, KYbus bus
    3. Drive from Oxmoor Center to Nicholasvillecar car
    9h 42m
    $74–126

  2. Drive 336.6 mi

    cheapest
    1. Drive from St. Louis to Nicholasvillecar car 336.6 mi
    5h 47m
    $62–89

  3. Fly to Blue Grass Airport

    1. Fly from Lambert–St. Louis International Airport (STL) to Blue Grass Airport (LEX)plane plane STL - LEX
    5h 50m
    $222–1,058

  4. Bus, drive

    1. Take the bus from St Louis Bus Station to Evansville Bus Stationbus bus
    2. Take the bus from Evansville, IN to Louisville, KYbus bus
    3. Drive from Oxmoor Center to Nicholasvillecar car
    9h 44m
    $74–126

  5. Bus, drive #2

    1. Take the bus from St Louis Bus Station to Evansville Bus Stationbus bus
    2. Take the bus from Evansville, IN to Louisville, KYbus bus
    3. Drive from Fern Valley @ Shepherdsville to Nicholasvillecar car
    9h 48m
    $75–127

  6. Fly to Louisville International Airport, drive

    1. Fly from Lambert–St. Louis International Airport (STL) to Louisville International Airport (SDF)plane plane STL - SDF
    2. Drive from Louisville-Airport-SDF to Nicholasvillecar car
    6h 24m
    $116–624

  7. Fly to Covington, drive

    1. Fly from Lambert–St. Louis International Airport (STL) to Covington (CVG)plane plane STL - CVG
    2. Drive from Covington (CVG) to Nicholasvillecar car
    6h 20m
    $138–726

Lambert–St. Louis International Airport (STL) to Blue Grass Airport (LEX) flights

Calendar101Weekly Planes
Duration4h 58mAverage Duration
Ticket$185Cheapest Price
See schedules

Questions & Answers

Map of how to get from St. Louis to Nicholasville.ExpandLaunch map view
  • Distance: 366 mi
  • Duration: 9h 42m

What companies run services between St. Louis, MO, USA and Nicholasville, KY, USA?

American Airlines, United Airlines, and Delta fly from Lambert–St. Louis International Airport (STL) to Blue Grass Airport (LEX) hourly.

Airlines
Bus operators

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