Rome2Rio

How to get fromSt. Louis to Nilesby plane, bus, train (Amtrak), train, car, subway, or bus (Flixbus)

Find Transport to Niles

See all options

There are 8 ways to get from St. Louis to Niles by plane, bus, train (Amtrak), train, car, subway, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Lambert–St. Louis International Airport to Chicago O'Hare International Airport, bus

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to Chicago O'Hare International Airport (ORD)plane plane STL - ORD
    2. Take the bus from Jefferson Park Transit Center to Harlem Stationbus bus
    3h 34m
    $276–710

  2. Drive 297.4 mi

    cheapest
    1. Drive from St. Louis to Nilescar car 297.4 mi
    5h 9m
    $55–79

  3. Train (Amtrak)

    1. Take the train from St. Louis to Chicago Union Stationtrain train Lincoln Service / ...
    6h 2m
    $95–193

  4. Train, bus

    1. Take the train from St. Louis to Bloomington-Normaltrain train Lincoln Service / ...
    2. Take the bus from Uptown Station to O'Hare Terminal 2 Departuresbus bus 1-Northbound / ...
    7h 32m

  5. Fly Lambert–St. Louis International Airport to Chicago Midway International Airport, subway, bus

    1. Fly from Lambert–St. Louis International Airport (STL) to Chicago Midway International Airport (MDW)plane plane STL - MDW
    2. Take the subway from Clark/Lake to Jefferson Parksubway subway
    3. Take the bus from Jefferson Park Transit Center to Harlem Stationbus bus
    4h 15m
    $62–376

  6. Train to Abraham Lincoln Capital Airport, fly to Chicago O'Hare International Airport

    1. Take the train from St. Louis to Springfieldtrain train
    2. Fly from Abraham Lincoln Capital Airport (SPI) to Chicago O'Hare International Airport (ORD)plane plane SPI - ORD
    4h 44m
    $77–307

  7. Bus to Williamson County Regional Airport, fly to Chicago O'Hare International Airport

    1. Take the bus from St. Louis to Carbondalebus bus
    2. Fly from Williamson County Regional Airport (MWA) to Chicago O'Hare International Airport (ORD)plane plane MWA - ORD
    5h 35m
    $134–314

  8. Bus

    1. Take the bus from St Louis Bus Station to Chicago Bus Stationbus bus FlixBus 2510 / ...
    7h 44m
    $56–93

St. Louis to Niles by train, foot, subway, and bus (Amtrak)

Calendar38Weekly Services
Duration6h 2mAverage Duration
Ticket$95Cheapest Price
See schedules

Questions & Answers

Map of how to get from St. Louis to Niles.ExpandLaunch map view
  • Distance: 284.6 mi
  • Duration: 3h 34m

What companies run services between St. Louis, MO, USA and Niles, IL, USA?

Amtrak operates a train from St. Louis to Chicago Union Station 5 times a day. Tickets cost $90–190 and the journey takes 4h 55m. Alternatively, FlixBus-us operates a bus from St Louis Bus Station to Chicago Bus Station 3 times a day, and the journey takes 6h 5m. Flixbus USA also services this route twice daily.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

More Questions & Answers