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How to get fromSt. Louis to North Carolinaby plane, bus (Flixbus, Greyhound), or car

Find Transport to North Carolina

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There are 9 ways to get from St. Louis to North Carolina by plane, bus (Flixbus, Greyhound), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Charlotte Douglas International Airport

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to Charlotte Douglas International Airport (CLT)plane plane STL - CLT
    3h 50m
    $116–706

  2. Fly to Fayetteville Municipal Airport

    cheapest
    1. Fly from Lambert–St. Louis International Airport (STL) to Fayetteville Municipal Airport (FAY)plane plane STL - FAY
    5h 20m
    $98–472

  3. Bus via Atlanta

    1. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus FlixBus N2521
    2. Take the bus from Atlanta Downtown to Charlotte Bus Stationbus bus FlixBus N2470
    15h 29m
    $126–208

  4. Drive  709.3 mi

    1. Drive from St. Louis to Charlottecar car 709.3 mi
    12h 4m
    $130–187

  5. Fly to Piedmont Triad International Airport

    1. Fly from Lambert–St. Louis International Airport (STL) to Piedmont Triad International Airport (GSO)plane plane STL - GSO
    5h 26m
    $110–488

  6. Fly to Wilmington International Airport

    1. Fly from Lambert–St. Louis International Airport (STL) to Wilmington International Airport (ILM)plane plane STL - ILM
    5h 28m
    $126–620

  7. Fly to Raleigh-Durham International Airport

    1. Fly from Lambert–St. Louis International Airport (STL) to Raleigh-Durham International Airport (RDU)plane plane STL - RDU
    4h 43m
    $106–606

  8. Bus

    1. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus FlixBus N2521
    2. Take the bus from Atlanta Bus Station to Charlotte Bus Stationbus bus Greyhound US0670 / ...
    15h 30m
    $123–210

  9. Bus via Sandy Springs

    1. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus FlixBus N2521
    2. Take the bus from Atlanta to Charlottebus bus Charlotte
    18h 25m
    $142–226

St. Louis to North Carolina by bus and subway

Calendar4Weekly Services
Duration15h 29mAverage Duration
Ticket$126Cheapest Price
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Comparing Your Travel Options

Map of how to get from St. Louis to North Carolina.ExpandLaunch map view
  • Distance: 595.2 mi
  • Duration: 3h 50m

What companies run services between St. Louis, MO, USA and North Carolina, USA?

American Airlines and Southwest Airlines fly from Lambert–St. Louis International Airport (STL) to Charlotte Douglas International Airport (CLT) every 3 hours. Alternatively, you can take a bus from St Louis Bus Station to Charlotte Bus Station via Atlanta Bus Station, Garnett Station, Civic Center Station, and Atlanta Downtown in around 15h 29m.

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