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How to get fromSt. Louis to Notre Dameby train (Amtrak), bus (Flixbus, Greyhound), car, plane, bus (Greyhound), or train

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There are 8 ways to get from St. Louis to Notre Dame by train (Amtrak), bus (Flixbus, Greyhound), car, plane, bus (Greyhound), or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train (Amtrak)

    best
    1. Take the train from St. Louis to Chicago Union Stationtrain train Lincoln Service / ...
    2. Take the train from Chicago Union Station to South Bend Stationtrain train Lake Shore Limited / ...
    7h 36m
    $115–237

  2. Drive  355.7 mi

    cheapest
    1. Drive from St. Louis to Notre Damecar car 355.7 mi
    6h 24m
    $65–94

  3. Bus

    1. Take the bus from St Louis Bus Station to Chicago Bus Stationbus bus FlixBus N2521 / ...
    2. Take the bus from Chicago to South Bend, INbus bus Chicago / ...
    8h 58m
    $73–119

  4. Fly to South Bend

    1. Fly from Lambert–St. Louis International Airport (STL) to South Bend (SBN)plane plane STL - SBN
    5h 11m
    $112–628

  5. Train via South Bend Airport

    1. Take the train from St. Louis to Chicago Union Stationtrain train Lincoln Service / ...
    2. Take the train from Van Buren St. to South Bend Airporttrain train Eastbound from Chicago / ...
    8h 25m
    $112–208

  6. Bus via Indianapolis

    1. Take the bus from St Louis Bus Station to Indianapolis Union Stationbus bus Greyhound US0421
    2. Take the bus from Indianapolis Union Station to South Street Station - South Bendbus bus South Bend
    8h 58m
    $92–241

  7. Fly to Chicago Midway International Airport, train

    1. Fly from Lambert–St. Louis International Airport (STL) to Chicago Midway International Airport (MDW)plane plane STL - MDW
    2. Take the train from Van Buren St. to South Bend Airporttrain train
    6h 39m
    $88–396

  8. Fly to Chicago O'Hare International Airport, train

    1. Fly from Lambert–St. Louis International Airport (STL) to Chicago O'Hare International Airport (ORD)plane plane STL - ORD
    2. Take the train from Van Buren St. to South Bend Airporttrain train
    7h 8m
    $358–746

Lambert–St. Louis International Airport (STL) to South Bend (SBN) flights

Calendar96Weekly Planes
Duration5h 8mAverage Duration
Ticket$91Cheapest Price
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Questions & Answers

Map of how to get from St. Louis to Notre Dame.ExpandLaunch map view
  • Distance: 368.6 mi
  • Duration: 7h 36m

What companies run services between St. Louis, MO, USA and Notre Dame, IN, USA?

You can take a train from St. Louis to Notre Dame via Chicago Union Station and South Bend Station in around 7h 36m. Alternatively, you can take a bus from St Louis Bus Station to Notre Dame via Chicago and South Bend, IN in around 8h 58m.

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