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How to get fromSt. Louis to Odessaby plane, bus (Greyhound), train, bus, or car

Find Transport to Odessa

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There are 5 ways to get from St. Louis to Odessa by plane, bus (Greyhound), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to Midland International Airport (MAF)plane plane STL - MAF
    5h 38m
    $148–598

  2. Bus

    1. Take the bus from St Louis Bus Station to Amarillo Multimodal Transfer Stabus bus
    2. Take the bus from Amarillo Multimodal Transfer Sta to Big Springbus bus
    3. Take the bus from Big Spring to Stripes gas station - Odessa, TXbus bus
    22h 43m
    $193–346

  3. Train, bus

    1. Take the train from St. Louis to Fort Worthtrain train Texas Eagle
    2. Take the bus from Fort Worth - La Gran Plaza to Stripes gas station - Odessa, TXbus bus Dallas
    24h 14m
    $307–576

  4. Drive 928.1 mi

    1. Drive from St. Louis to Odessacar car 928.1 mi
    15h 44m
    $170–245

  5. Train, bus via Fort Worth

    1. Take the train from St. Louis to Fort Worthtrain train Texas Eagle
    2. Take the bus from Fort Worth, TX - Tornado Bus Co to Odessa, TX - Stripes Gas Stationbus bus Dallas
    25h 5m
    $307–666

Lambert–St. Louis International Airport (STL) to Midland International Airport (MAF) flights

Calendar74Weekly Planes
Duration4h 51mAverage Duration
Ticket$110Cheapest Price
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Questions & Answers

Map of how to get from St. Louis to Odessa.ExpandLaunch map view
  • Distance: 841.5 mi
  • Duration: 5h 38m

What companies run services between St. Louis, MO, USA and Odessa, TX, USA?

Southwest Airlines, American Airlines, and United Airlines fly from Lambert–St. Louis International Airport (STL) to Midland International Airport (MAF) every 2 hours. Alternatively, you can take a bus from St Louis Bus Station to Stripes gas station - Odessa, TX via Amarillo Multimodal Transfer Sta and Big Spring in around 22h 43m.

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