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How to get fromSt. Louis to Opelikaby plane, taxi, bus (Amtrak, Flixbus, Greyhound), car, bus, or bus (Greyhound, Flixbus)

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There are 5 ways to get from St. Louis to Opelika by plane, taxi, bus (Amtrak, Flixbus, Greyhound), car, bus, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Columbus Airport, taxi

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to Columbus Airport (CSG)plane plane STL - CSG
    2. Take the taxi from Columbus Airport (CSG) to Opelikataxi taxi
    5h 29m
    $148–518

  2. Bus via Carbondale

    cheapest
    1. Take the bus from St. Louis to Carbondalebus bus
    2. Take the bus from Carbondale Intermodal Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Opelika 4th Street Stationbus bus
    14h 55m
    $101–183

  3. Drive  594.1 mi

    1. Drive from St. Louis to Opelikacar car 594.1 mi
    10h 32m
    $109–157

  4. Fly to Hartsfield-Jackson Atlanta International Airport, bus

    1. Fly from Lambert–St. Louis International Airport (STL) to Hartsfield-Jackson Atlanta International Airport (ATL)plane plane STL - ATL
    2. Take the bus from Atlanta Airport to Comfort Inn - Opelikabus bus
    5h 39m
    $132–624

  5. Bus

    1. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus Greyhound US0186
    2. Take the bus from Atlanta Bus Station to Opelika 4th Street Stationbus bus Greyhound US0602 / ...
    15h 30m
    $106–174

St. Louis to Opelika by bus

Calendar5Weekly Buses
Duration14h 55mAverage Duration
Ticket$101Cheapest Price
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Questions & Answers

Map of how to get from St. Louis to Opelika.ExpandLaunch map view
  • Distance: 571.7 mi
  • Duration: 5h 29m

What companies run services between St. Louis, MO, USA and Opelika, AL, USA?

You can take a bus from St. Louis to Opelika 4th Street Station via Carbondale Intermodal Station and Atlanta Bus Station in around 14h 55m.

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