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How to get fromSt. Louis to Orangeburgby plane, taxi, bus (Greyhound, Flixbus), car, bus, or bus (Greyhound)

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There are 7 ways to get from St. Louis to Orangeburg by plane, taxi, bus (Greyhound, Flixbus), car, bus, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Columbia, taxi

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to Columbia (CAE)plane plane STL - CAE
    2. Take the taxi from Columbia-Airport-CAE to Orangeburgtaxi taxi
    6h 3m
    $352–1,352

  2. Fly to Augusta Regional Airport At Bush Field, drive

    cheapest
    1. Fly from Lambert–St. Louis International Airport (STL) to Augusta Regional Airport At Bush Field (AGS)plane plane STL - AGS
    2. Drive from Augusta Regional Airport At Bush Field (AGS) to Orangeburgcar car
    6h 59m
    $106–504

  3. Bus

    1. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta to Savannahbus bus
    3. Take the bus from Savannah Bus Station to Orangeburgbus bus
    19h 3m
    $174–302

  4. Drive 773.9 mi

    1. Drive from St. Louis to Orangeburgcar car 773.9 mi
    13h 4m
    $142–204

  5. Fly to Savannah, bus

    1. Fly from Lambert–St. Louis International Airport (STL) to Savannah (SAV)plane plane STL - SAV
    2. Take the bus from Savannah Bus Station to Orangeburgbus bus
    6h 50m
    $198–802

  6. Fly to Myrtle Beach, bus

    1. Fly from Lambert–St. Louis International Airport (STL) to Myrtle Beach (MYR)plane plane STL - MYR
    2. Take the bus from Myrtle Beach Bus Station to Orangeburgbus bus
    8h 20m
    $134–522

  7. Bus via Evansville

    1. Take the bus from St Louis Bus Station to Evansville Bus Stationbus bus
    2. Take the bus from Evansville Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta to Orangeburgbus bus
    20h 18m
    $221–344

Lambert–St. Louis International Airport (STL) to Columbia (CAE) flights

Calendar131Weekly Planes
Duration5h 25mAverage Duration
Ticket$233Cheapest Price
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Questions & Answers

Map of how to get from St. Louis to Orangeburg.ExpandLaunch map view
  • Distance: 664.6 mi
  • Duration: 6h 3m

What companies run services between St. Louis, MO, USA and Orangeburg, SC, USA?

You can take a bus from St Louis Bus Station to Orangeburg via Atlanta, Savannah, Savannah Bus Station, and Orangeburg in around 19h 3m.

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Bus operators
Other operators

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