Rome2Rio

How to get fromSt. Louis to Palo Altoby plane, bus (Greyhound, Flixbus), train, bus, subway, car, or train (Amtrak)

Find Transport to Palo Alto

See all options

There are 7 ways to get from St. Louis to Palo Alto by plane, bus (Greyhound, Flixbus), train, bus, subway, car, or train (Amtrak)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to San Francisco International Airport

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to San Francisco International Airport (SFO)plane plane STL - SFO
    6h 45m
    $156–410

  2. Bus

    1. Take the bus from St Louis Bus Station to Los Angeles Union Stationbus bus Greyhound US1210
    2. Take the bus from Los Angeles Union Station to San Jose Diridon Stationbus bus Greyhound US0831 / ...
    2d
    $351–556

  3. Train, bus, BART

    1. Take the train from St. Louis to Bloomington-Normaltrain train
    2. Take the bus from Bloomington-Normal to Galesburgbus bus
    3. Take the train from Galesburg Amtrak Station to Richmondtrain train
    4. Take the subway from Richmond to Millbraesubway subway
    2d 10h
    $621–1,433

  4. Drive  2,073.3 mi

    1. Drive from St. Louis to Palo Altocar car 2,073.3 mi
    32h 26m
    $379–547

  5. Fly to Norman Y. Mineta San José International Airport

    1. Fly from Lambert–St. Louis International Airport (STL) to Norman Y. Mineta San José International Airport (SJC)plane plane STL - SJC
    8h 12m
    $170–762

  6. Fly to Oakland International Airport, train

    1. Fly from Lambert–St. Louis International Airport (STL) to Oakland International Airport (OAK)plane plane STL - OAK
    2. Take the train from Oakland Coliseum/Airport Amtrak to Santa Clara Amtraktrain train
    9h 55m
    $188–782

  7. Train (Amtrak)

    1. Take the train from St. Louis to Los Angelestrain train Texas Eagle
    2. Take the train from Los Angeles to San Josetrain train Coast Starlight
    2d 23h
    $733–1,627

St. Louis to Palo Alto by bus and train

Calendar7Weekly Services
Duration2dAverage Duration
Ticket$351Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from St. Louis to Palo Alto.ExpandLaunch map view
  • Distance: 1,766.3 mi
  • Duration: 6h 45m

What companies run services between St. Louis, MO, USA and Palo Alto, CA, USA?

United Airlines, Southwest Airlines, and two other airlines fly from Lambert–St. Louis International Airport (STL) to San Francisco International Airport (SFO) every 3 hours. Alternatively, you can take a bus from St Louis Bus Station to California Avenue Caltrain Northbound via Los Angeles Union Station, San Jose Diridon Station, and San Jose Diridon Caltrain Northbound in around 2d.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Booking & Getting There