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How to get fromSt. Louis to Panama Cityby plane, car, or bus

Find Transport to Panama City

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There are 3 ways to get from St. Louis to Panama City by plane, car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Lambert–St. Louis International Airport

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to Tocumen International Airport (PTY)plane plane STL - PTY
    9h 59m
    $210–790

  2. Drive  5,583.9 km

    1. Drive from St. Louis to Panama Citycar car 5,583.9 km
    3d
    $714–1,031

  3. Bus to Decatur Airport, fly

    1. Take the bus from St Louis Bus Station to Decatur Downtown Transportation Centerbus bus
    2. Fly from Decatur Airport (DEC) to Tocumen International Airport (PTY)plane plane DEC - PTY
    16h 3m
    $234–787

Lambert–St. Louis International Airport (STL) to Tocumen International Airport (PTY) flights

Calendar39Weekly Planes
Duration7h 3mAverage Duration
Ticket$177Cheapest Price
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Comparing Your Travel Options

Map of how to get from St. Louis to Panama City.ExpandLaunch map view
  • Distance: 3,523.5 km
  • Duration: 9h 59m

What companies run services between St. Louis, MO, USA and Panama City, Panama?

Delta, American Airlines, and three other airlines fly from Lambert–St. Louis International Airport (STL) to Tocumen International Airport (PTY) every 4 hours.

Airlines
Bus operators

Want to know more about travelling around Panama

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