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How to get fromSt. Louis to Panama Cityby plane, car, or bus

Find Transport to Panama City

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There are 3 ways to get from St. Louis to Panama City by plane, car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Lambert–St. Louis International Airport

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to Tocumen International Airport (PTY)plane plane STL - PTY
    10h 7m
    $210–740

  2. Drive  5,583.9 km

    1. Drive from St. Louis to Panama Citycar car 5,583.9 km
    3d
    $764–1,104

  3. Bus to Decatur Airport, fly

    1. Take the bus from St Louis Bus Station to Decatur Downtown Transportation Centerbus bus
    2. Fly from Decatur Airport (DEC) to Tocumen International Airport (PTY)plane plane DEC - PTY
    16h 43m
    $233–786

Lambert–St. Louis International Airport (STL) to Tocumen International Airport (PTY) flights

Calendar26Weekly Planes
Duration7h 14mAverage Duration
Ticket$172Cheapest Price
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Comparing Your Travel Options

Map of how to get from St. Louis to Panama City.ExpandLaunch map view
  • Distance: 3,523.5 km
  • Duration: 10h 7m

What companies run services between St. Louis, MO, USA and Panama City, Panama?

Delta, American Airlines, and two other airlines fly from Lambert–St. Louis International Airport (STL) to Tocumen International Airport (PTY) 4 times a day.

Airlines
Bus operators

Want to know more about travelling around Panama

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