There are 3 ways to get from St. Louis to Panama by plane or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Tocumen International Airport
best- Fly from Lambert–St. Louis International Airport (STL) to Tocumen International Airport (PTY)plane STL - PTY
10h 6m$322–792Fly to Panama Pacific International Airport
cheapest- Fly from Lambert–St. Louis International Airport (STL) to Panama Pacific International Airport (BLB)plane STL - BLB
19h 35m$180–774Drive 5,586.1 km
- Drive from St. Louis to Panama Citycar 5,586.1 km
3d$765–1,104
Lambert–St. Louis International Airport (STL) to Tocumen International Airport (PTY) flights
Questions & Answers
The cheapest way to get from St. Louis to Panama is to fly which costs $180 - $800 and takes 19h 35m.
The fastest way to get from St. Louis to Panama is to fly which takes 10h 6m and costs $320 - $800.
The distance between St. Louis and Panama is 3522 km. The road distance is 5586.1 km.
It takes approximately 10h 6m to get from St. Louis to Panama, including transfers.
Yes, the driving distance between St. Louis to Panama is 5586 km. It takes approximately 3 days 0h to drive from St. Louis to Panama.
There are 926+ hotels available in Panama.
What companies run services between St. Louis, MO, USA and Panama?
Delta, American Airlines, and three other airlines fly from Lambert–St. Louis International Airport (STL) to Tocumen International Airport (PTY) 4 times a day.
- Website
- copaair.com
Flights from Lambert–St. Louis International Airport to Panama Pacific International Airport via Miami, Havana
- Ave. Duration
- 20h 35m
- When
- Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $230–950
Flights from Lambert–St. Louis International Airport to Panama Pacific International Airport via Atlanta, Cartagena
- Ave. Duration
- 28h 3m
- When
- Saturday
- Estimated price
- $250–1,000
Flights from Lambert–St. Louis International Airport to Panama Pacific International Airport via Tampa, Havana
- Ave. Duration
- 30h 15m
- When
- Thursday and Friday
- Estimated price
- $160–750
Flights from Lambert–St. Louis International Airport to Panama Pacific International Airport via Cancun, Medellin Jose Marie Cordova
- Ave. Duration
- 23h 12m
- When
- Saturday
- Estimated price
- $470–1,500
Flights from Lambert–St. Louis International Airport to Panama Pacific International Airport via Orlando, Medellin Jose Marie Cordova
- Ave. Duration
- 23h 32m
- When
- Saturday
- Estimated price
- $460–1,500
Flights from Lambert–St. Louis International Airport to Panama Pacific International Airport via Cancun, Havana
- Ave. Duration
- 26h 45m
- When
- Thursday, Friday, and Sunday
- Estimated price
- $260–1,000
- Website
- copaair.com
Flights from Lambert–St. Louis International Airport to Tocumen International Airport via Miami
- Ave. Duration
- 6h 58m
- When
- Monday, Thursday, Friday, Tuesday, and Sunday
- Estimated price
- $200–850
Flights from Lambert–St. Louis International Airport to Tocumen International Airport via Orlando
- Ave. Duration
- 7h
- When
- Monday and Saturday
- Estimated price
- $200–850
Flights from Lambert–St. Louis International Airport to Tocumen International Airport via Cancun
- Ave. Duration
- 6h 56m
- When
- Every day
- Estimated price
- $280–750
- Website
- delta.com
Flights from Lambert–St. Louis International Airport to Tocumen International Airport via Atlanta
- Ave. Duration
- 6h 55m
- When
- Every day
- Estimated price
- $200–850
- Website
- aa.com
Flights from Lambert–St. Louis International Airport to Tocumen International Airport via Miami
- Ave. Duration
- 7h 39m
- When
- Every day
- Estimated price
- $200–850
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