There are 2 ways to get from St. Louis to Panama by plane or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Lambert–St. Louis International Airport (STL) to Tocumen International Airport (PTY) flights
Comparing Your Travel Options
The cheapest way to get from St. Louis to Panama is to fly which costs $210 - $800 and takes 9h 46m.
The fastest way to get from St. Louis to Panama is to fly which takes 9h 46m and costs $210 - $800.
The distance between St. Louis and Panama is 3522 km. The road distance is 5583.9 km.
It takes approximately 9h 46m to get from St. Louis to Panama, including transfers.
Yes, the driving distance between St. Louis to Panama is 5584 km. It takes approximately 3 days 0h to drive from St. Louis to Panama.
There are 877+ hotels available in Panama.
What companies run services between St. Louis, MO, USA and Panama?
American Airlines, Delta, and two other airlines fly from Lambert–St. Louis International Airport (STL) to Tocumen International Airport (PTY) 3 times a day.
- Website
- copaair.com
Flights from Lambert–St. Louis International Airport to Tocumen International Airport via Tampa
- Ave. Duration
- 6h 30m
- When
- Monday to Friday
- Estimated price
- $170–750
Flights from Lambert–St. Louis International Airport to Tocumen International Airport via Orlando
- Ave. Duration
- 6h 50m
- When
- Monday, Thursday, Friday, and Saturday
- Estimated price
- $170–750
Flights from Lambert–St. Louis International Airport to Tocumen International Airport via Miami
- Ave. Duration
- 6h 46m
- When
- Saturday
- Estimated price
- $170–750
Flights from Lambert–St. Louis International Airport to Tocumen International Airport via Cancun
- Ave. Duration
- 7h 3m
- When
- Sunday
- Estimated price
- $170–750
- Website
- aa.com
Flights from Lambert–St. Louis International Airport to Tocumen International Airport via Miami
- Ave. Duration
- 6h 48m
- When
- Sunday
- Estimated price
- $170–750
- Website
- delta.com
Flights from Lambert–St. Louis International Airport to Tocumen International Airport via Atlanta
- Ave. Duration
- 6h 59m
- When
- Every day
- Estimated price
- $170–750
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