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How to get fromSt. Louis to Pensacolaby plane, bus, train, bus (Greyhound, Flixbus), car, or taxi

Find Transport to Pensacola

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There are 7 ways to get from St. Louis to Pensacola by plane, bus, train, bus (Greyhound, Flixbus), car, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Lambert–St. Louis International Airport to Pensacola International Airport

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to Pensacola International Airport (PNS)plane plane STL - PNS
    4h 22m
    $70–394

  2. Bus, train

    1. Take the bus from St Louis Bus Station to Carbondale Intermodal Stationbus bus
    2. Take the train from Carbondale to New Orleans Union Passenger Terminaltrain train
    3. Take the train from New Orleans Union Passenger Terminal to Gulfport Amtrak Statrain train
    4. Take the bus from Gulfport to Pensacolabus bus
    21h 51m
    $440–697

  3. Bus

    1. Take the bus from St Louis Bus Station to New Orleans Bus Stationbus bus
    2. Take the bus from New Orleans Bus Station to Biloxi Transit Centerbus bus
    3. Take the bus from Biloxi to Pensacolabus bus
    22h 50m
    $194–286

  4. Drive  699.1 mi

    1. Drive from St. Louis to Pensacolacar car 699.1 mi
    12h 47m
    $120–173

  5. Fly Lambert–St. Louis International Airport to Destin–Fort Walton Beach Airport, taxi

    1. Fly from Lambert–St. Louis International Airport (STL) to Destin–Fort Walton Beach Airport (VPS)plane plane STL - VPS
    2. Take the taxi from Destin–Fort Walton Beach Airport (VPS) to Pensacolataxi taxi
    4h 36m
    $202–602

  6. Fly Midamerica St. Louis Airport to Destin–Fort Walton Beach Airport, taxi

    1. Fly from Midamerica St. Louis Airport (BLV) to Destin–Fort Walton Beach Airport (VPS)plane plane BLV - VPS
    2. Take the taxi from Destin–Fort Walton Beach Airport (VPS) to Pensacolataxi taxi
    4h 47m
    $210–560

  7. Fly Lambert–St. Louis International Airport to Northwest Florida Beaches International Airport, drive

    1. Fly from Lambert–St. Louis International Airport (STL) to Northwest Florida Beaches International Airport (ECP)plane plane STL - ECP
    2. Drive from Northwest Florida Beaches International Airport (ECP) to Pensacolacar car
    5h 42m
    $100–478

Lambert–St. Louis International Airport (STL) to Pensacola International Airport (PNS) flights

Calendar19Weekly Planes
Duration3h 30mAverage Duration
Ticket$69Cheapest Price
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Comparing Your Travel Options

Map of how to get from St. Louis to Pensacola.ExpandLaunch map view
  • Distance: 617.3 mi
  • Duration: 4h 22m

What companies run services between St. Louis, MO, USA and Pensacola, FL, USA?

Southwest Airlines and Delta fly from Lambert–St. Louis International Airport (STL) to Pensacola International Airport (PNS) 3 times a day. Alternatively, you can take a bus from St Louis Bus Station to Pensacola via New Orleans Bus Station, Biloxi Transit Center, and Biloxi in around 22h 50m.

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