There are 7 ways to get from St. Louis to Philadelphia by bus, taxi, train, car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus, taxi
best- Take the bus from St Louis Bus Station to Memphis Bus Stationbus
- Take the bus from Memphis Bus Station to Meridian Bus Stopbus
- Take the taxi from Meridian Bus Stop to Philadelphiataxi
11h 48m$192–280Drive 474.7 mi
cheapest- Drive from St. Louis to Philadelphiacar 474.7 mi
8h 12m$84–122Bus, train, taxi
- Take the bus from St Louis Bus Station to Carbondale Intermodal Stationbus
- Take the train from Carbondale to Jacksontrain
- Take the bus from Jackson to Meridian Bus Stopbus
- Take the taxi from Meridian Bus Stop to Philadelphiataxi
16h 4m$382–569Fly to Jackson/Vicksburg, drive
- Fly from Lambert–St. Louis International Airport (STL) to Jackson/Vicksburg (JAN)plane STL - JAN
- Drive from Jackson/Vicksburg (JAN) to Philadelphiacar
7h 16m$96–472Fly to Golden Triangle Regional Airport, drive
- Fly from Lambert–St. Louis International Airport (STL) to Golden Triangle Regional Airport (GTR)plane STL - GTR
- Drive from Golden Triangle Regional Airport (GTR) to Philadelphiacar
6h 53m$100–492Fly to Meridian, taxi
- Fly from Lambert–St. Louis International Airport (STL) to Meridian (MEI)plane STL - MEI
- Take the taxi from Meridian (MEI) to Philadelphiataxi
7h 15m$222–692Fly to Birmingham–Shuttlesworth International Airport, drive
- Fly from Lambert–St. Louis International Airport (STL) to Birmingham–Shuttlesworth International Airport (BHM)plane STL - BHM
- Drive from Birmingham-Airport-BHM to Philadelphiacar
8h 13m$182–948
Lambert–St. Louis International Airport (STL) to Jackson/Vicksburg (JAN) flights
Comparing Your Travel Options
The cheapest way to get from St. Louis to Philadelphia is to drive which costs $80 - $130 and takes 8h 12m.
The fastest way to get from St. Louis to Philadelphia is to fly and drive which takes 6h 53m and costs $95 - $500.
The distance between St. Louis and Philadelphia is 569 miles. The road distance is 477.5 miles.
The best way to get from St. Louis to Philadelphia without a car is to bus and taxi which takes 11h 48m and costs $190 - $280.
It takes approximately 11h 48m to get from St. Louis to Philadelphia, including transfers.
Yes, the driving distance between St. Louis to Philadelphia is 477 miles. It takes approximately 8h 12m to drive from St. Louis to Philadelphia.
What companies run services between St. Louis, MO, USA and Philadelphia, MS, USA?
There is no direct connection from St. Louis to Philadelphia. However, you can take the bus to Memphis Bus Station, take the bus to Meridian Bus Stop, then take the taxi to Philadelphia. Alternatively, you can take the bus to Carbondale Intermodal Station, walk to Carbondale, take the train to Jackson, walk to Jackson, take the bus to Meridian Bus Stop, then take the taxi to Philadelphia.
- Website
- delta.com
Flights from Lambert–St. Louis International Airport to Jackson/Vicksburg via Atlanta
- Ave. Duration
- 4h 32m
- When
- Every day
- Estimated price
- $95–490
Flights from Lambert–St. Louis International Airport to Golden Triangle Regional Airport via Atlanta
- Ave. Duration
- 3h 58m
- When
- Every day
- Estimated price
- $85–470
Flights from Lambert–St. Louis International Airport to Birmingham–Shuttlesworth International Airport via Atlanta
- Ave. Duration
- 4h 1m
- When
- Every day
- Estimated price
- $170–1,000
Flights from Lambert–St. Louis International Airport to Birmingham–Shuttlesworth International Airport via Detroit
- Ave. Duration
- 6h 33m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $240–1,200
- Website
- aa.com
Flights from Lambert–St. Louis International Airport to Jackson/Vicksburg via Charlotte
- Ave. Duration
- 6h 1m
- When
- Thursday, Friday, and Sunday
- Estimated price
- $110–600
Flights from Lambert–St. Louis International Airport to Jackson/Vicksburg via Dallas/Ft.Worth
- Ave. Duration
- 5h 54m
- When
- Every day
- Estimated price
- $100–550
Flights from Lambert–St. Louis International Airport to Jackson/Vicksburg via Reagan Washington
- Ave. Duration
- 5h 57m
- When
- Sunday
- Estimated price
- $140–650
Flights from Lambert–St. Louis International Airport to Golden Triangle Regional Airport via Dallas/Ft.Worth
- Ave. Duration
- 5h 24m
- When
- Every day
- Estimated price
- $110–550
Flights from Lambert–St. Louis International Airport to Birmingham–Shuttlesworth International Airport via Charlotte
- Ave. Duration
- 5h 54m
- When
- Every day
- Estimated price
- $220–1,200
Flights from Lambert–St. Louis International Airport to Birmingham–Shuttlesworth International Airport via Chicago O'Hare
- Ave. Duration
- 5h 48m
- When
- Every day
- Estimated price
- $210–1,100
- Website
- southwest.com
Flights from Lambert–St. Louis International Airport to Jackson/Vicksburg via Nashville
- Ave. Duration
- 5h 47m
- When
- Saturday, Tuesday, and Wednesday
- Estimated price
- $80–450
Flights from Lambert–St. Louis International Airport to Jackson/Vicksburg via Houston Hobby Apt
- Ave. Duration
- 7h 25m
- When
- Every day
- Estimated price
- $110–550
Flights from Lambert–St. Louis International Airport to Birmingham–Shuttlesworth International Airport via Chicago Midway
- Ave. Duration
- 4h 50m
- When
- Saturday, Tuesday, and Wednesday
- Estimated price
- $210–1,100
Flights from Lambert–St. Louis International Airport to Birmingham–Shuttlesworth International Airport via Nashville
- Ave. Duration
- 4h 58m
- When
- Every day
- Estimated price
- $150–900
Flights from Lambert–St. Louis International Airport to Birmingham–Shuttlesworth International Airport via Dallas
- Ave. Duration
- 5h 17m
- When
- Monday, Tuesday, Wednesday, and Saturday
- Estimated price
- $250–1,300
- Website
- united.com
Flights from Lambert–St. Louis International Airport to Jackson/Vicksburg via Houston
- Ave. Duration
- 5h 13m
- When
- Every day
- Estimated price
- $100–550
Flights from Lambert–St. Louis International Airport to Meridian via Houston
- Ave. Duration
- 7h 34m
- When
- Every day
- Estimated price
- $110–550
Flights from Lambert–St. Louis International Airport to Birmingham–Shuttlesworth International Airport via Chicago O'Hare
- Ave. Duration
- 4h 42m
- When
- Every day
- Estimated price
- $210–1,100
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Carbondale to Jackson
- Ave. Duration
- 9h 46m
- Frequency
- Once daily
- Estimated price
- $240–380
- Website
- Amtrak
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from St Louis Bus Station to Memphis Bus Station
- Ave. Duration
- 5h 30m
- Frequency
- Twice daily
- Estimated price
- $50–80
- Website
- Greyhound
Bus from Jackson to Meridian Bus Stop
- Ave. Duration
- 1h 30m
- Frequency
- 4 times a day
- Estimated price
- $17–26
- Website
- Greyhound
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from St Louis Bus Station to Memphis Bus Station
- Ave. Duration
- 4h 45m
- Frequency
- Once daily
- Estimated price
- $45–70
- Schedules at
- Flixbus USA
Bus from Memphis Bus Station to Meridian Bus Stop
- Ave. Duration
- 4h 20m
- Frequency
- Once daily
- Estimated price
- $35–60
- Schedules at
- Flixbus USA
Bus from St Louis Bus Station to Carbondale Intermodal Station
- Ave. Duration
- 1h 50m
- Frequency
- Once daily
- Estimated price
- $15–23
- Schedules at
- Flixbus USA
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from St Louis Bus Station to Carbondale Intermodal Station
- Ave. Duration
- 2h
- Frequency
- Once daily
- Website
- Amtrak
- Ave. Duration
- 58 min
- Estimated price
- $110–140
Meridian Cab
- Phone
- +1 601-693-6339
Meridian Cab
- Phone
- +1 601-693-6339
Meridian Cab
- Phone
- +1 601-693-6339
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