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How to get fromSt. Louis to Plymouthby plane, bus, train, bus (Flixbus, Greyhound), car, or taxi

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There are 8 ways to get from St. Louis to Plymouth by plane, bus, train, bus (Flixbus, Greyhound), car, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to General Mitchell International Airport, bus

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to General Mitchell International Airport (MKE)plane plane STL - MKE
    2. Take the bus from Milwaukee Intermodal Station to Sheboyganbus bus
    5h 35m
    $524–938

  2. Drive 419.6 mi

    cheapest
    1. Drive from St. Louis to Plymouthcar car 419.6 mi
    7h 21m
    $77–111

  3. Train, bus via Milwaukee

    1. Take the train from St. Louis to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Milwaukeetrain train
    3. Take the bus from Milwaukee Intermodal Station to Sheboyganbus bus
    9h 42m
    $157–316

  4. Bus

    1. Take the bus from St Louis Bus Station to Chicago Bus Stationbus bus FlixBus N2521 / ...
    2. Take the bus from Chicago Bus Station to Sheboyganbus bus Greyhound US0150S
    10h 58m
    $103–174

  5. Fly to Appleton International Airport, taxi

    1. Fly from Lambert–St. Louis International Airport (STL) to Appleton International Airport (ATW)plane plane STL - ATW
    2. Take the taxi from Appleton International Airport (ATW) to Plymouthtaxi taxi
    6h 48m
    $252–1,002

  6. Fly to Green Bay, bus

    1. Fly from Lambert–St. Louis International Airport (STL) to Green Bay (GRB)plane plane STL - GRB
    2. Take the bus from Green Bay Transit Center to Sheboyganbus bus
    8h 20m
    $150–550

  7. Fly to Chicago O'Hare International Airport, bus

    1. Fly from Lambert–St. Louis International Airport (STL) to Chicago O'Hare International Airport (ORD)plane plane STL - ORD
    2. Take the bus from Chicago to Sheboyganbus bus
    7h 24m
    $324–792

  8. Train, bus

    1. Take the train from St. Louis to Chicago Union Stationtrain train Lincoln Service / ...
    2. Take the bus from Chicago Bus Station to Sheboyganbus bus Greyhound US0150S
    9h 57m
    $142–275

Lambert–St. Louis International Airport (STL) to General Mitchell International Airport (MKE) flights

Calendar17Weekly Planes
Duration1h 30mAverage Duration
Ticket$89Cheapest Price
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Questions & Answers

Map of how to get from St. Louis to Plymouth.ExpandLaunch map view
  • Distance: 408.4 mi
  • Duration: 5h 35m

What companies run services between St. Louis, MO, USA and Plymouth, WI, USA?

You can take a bus from St Louis Bus Station to Plymouth via Chicago Bus Station and Sheboygan in around 10h 58m.

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