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How to get fromSt. Louis to Portsmouthby plane, bus, train, bus (Greyhound, Flixbus), or car

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There are 7 ways to get from St. Louis to Portsmouth by plane, bus, train, bus (Greyhound, Flixbus), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Boston Logan Airport, bus

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to Boston Logan Airport (BOS)plane plane STL - BOS
    2. Take the bus from Boston to Portsmouthbus bus
    6h 51m
    $378–880

  2. Fly to Theodore Francis Green State Airport, train, bus

    cheapest
    1. Fly from Lambert–St. Louis International Airport (STL) to Theodore Francis Green State Airport (PVD)plane plane STL - PVD
    2. Take the train from TF Green Airport to South Stationtrain train
    3. Take the bus from Boston to Portsmouth Bus Stopbus bus
    10h 27m
    $110–466

  3. Train, bus

    1. Take the train from St. Louis to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Bostontrain train
    3. Take the bus from Boston to Portsmouth Bus Stopbus bus
    29h 57m
    $405–901

  4. Bus

    1. Take the bus from St Louis Bus Station to Port Authority Bus Terminalbus bus Greyhound US0421
    2. Take the bus from New York Midtown to Portsmouth Bus Stopbus bus FlixBus N2615
    32h 12m
    $198–373

  5. Drive 1,199.7 mi

    1. Drive from St. Louis to Portsmouthcar car 1,199.7 mi
    21h 18m
    $219–317

  6. Fly to Portland, bus

    1. Fly from Lambert–St. Louis International Airport (STL) to Portland (PWM)plane plane STL - PWM
    2. Take the bus from City of Portland to Portsmouth Bus Stopbus bus
    8h 51m
    $152–722

  7. Fly to Manchester Airport, bus

    1. Fly from Lambert–St. Louis International Airport (STL) to Manchester Airport (MHT)plane plane STL - MHT
    2. Take the bus from Boston Manchester Airport to Bostonbus bus
    3. Take the bus from Boston to Portsmouth Bus Stopbus bus
    10h 26m
    $148–684

St. Louis to Portsmouth by train and bus

Calendar7Weekly Services
Duration29h 57mAverage Duration
Ticket$405Cheapest Price
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Questions & Answers

Map of how to get from St. Louis to Portsmouth.ExpandLaunch map view
  • Distance: 1,114.7 mi
  • Duration: 6h 51m

What companies run services between St. Louis, MO, USA and Portsmouth, NH, USA?

You can take a bus from St Louis Bus Station to Portsmouth Bus Stop via Port Authority Bus Terminal and New York Midtown in around 32h 12m.

Airlines
Train operators
Bus operators

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