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How to get fromSt. Louis to San Luis Obispoby plane, bus (Greyhound, Flixbus), train (Amtrak), car, or bus

Find Transport to San Luis Obispo

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There are 6 ways to get from St. Louis to San Luis Obispo by plane, bus (Greyhound, Flixbus), train (Amtrak), car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to San Luis Obispo County Regional Airport

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to San Luis Obispo County Regional Airport (SBP)plane plane STL - SBP
    8h 28m
    $134–554

  2. Bus

    1. Take the bus from St Louis Bus Station to Los Angeles Union Stationbus bus Greyhound US1210
    2. Take the bus from Los Angeles Union Station to San Luis Obispo Railroad Museumbus bus FlixBus 2005
    45h 30m
    $319–602

  3. Train via Kansas City (Amtrak)

    1. Take the train from St. Louis to Kansas Citytrain train
    2. Take the train from Kansas City to Los Angelestrain train
    3. Take the train from Los Angeles to San Luis Obispotrain train
    2d
    $710–1,533

  4. Drive 1,950.6 mi

    1. Drive from St. Louis to San Luis Obispocar car 1,950.6 mi
    31h 20m
    $356–515

  5. Fly to Santa Barbara Municipal Airport, bus

    1. Fly from Lambert–St. Louis International Airport (STL) to Santa Barbara Municipal Airport (SBA)plane plane STL - SBA
    2. Take the bus from Uc Santa Barbara Amtrak Bus Stop to San Luis Obispobus bus
    11h
    $184–704

  6. Train (Amtrak)

    1. Take the train from St. Louis to Los Angelestrain train Texas Eagle
    2. Take the train from Los Angeles to San Luis Obispotrain train Coast Starlight / ...
    2d 17h
    $856–1,752

St. Louis to San Luis Obispo by bus

Calendar4Weekly Buses
Duration45h 30mAverage Duration
Ticket$319Cheapest Price
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Questions & Answers

Map of how to get from St. Louis to San Luis Obispo.ExpandLaunch map view
  • Distance: 1,698.2 mi
  • Duration: 8h 28m

What companies run services between St. Louis, MO, USA and San Luis Obispo, CA, USA?

American Airlines and United Airlines fly from Lambert–St. Louis International Airport (STL) to San Luis Obispo County Regional Airport (SBP) every 4 hours. Alternatively, you can take a bus from St Louis Bus Station to San Luis Obispo Railroad Museum via Los Angeles Union Station in around 45h 30m.

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