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How to get fromSt. Louis to Sanibelby plane, bus, taxi, car, or train

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There are 5 ways to get from St. Louis to Sanibel by plane, bus, taxi, car, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Lambert–St. Louis International Airport to Ft. Myers

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to Ft. Myers (RSW)plane plane STL - RSW
    4h 38m
    $208–748

  2. Drive 1,125 mi

    cheapest
    1. Drive from St. Louis to Sanibelcar car 1,125 mi
    19h 30m
    $206–297

  3. Bus, taxi

    1. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Gainesvillebus bus
    3. Take the bus from University of Florida - 1956 Gale Lemerand Dr to Fort Myers 7-11bus bus
    4. Take the taxi from Fort Myers 7-11 to Sanibeltaxi taxi
    25h 31m
    $276–470

  4. Fly Midamerica St. Louis Airport to Punta Gorda Airport, taxi

    1. Fly from Midamerica St. Louis Airport (BLV) to Punta Gorda Airport (PGD)plane plane BLV - PGD
    2. Take the taxi from Punta Gorda Airport (PGD) to Sanibeltaxi taxi
    5h 24m
    $236–620

  5. Bus, train

    1. Take the bus from St Louis Bus Station to New Orleans Bus Stationbus bus
    2. Take the train from New Orleans Union Passenger Terminal to Gulfport Amtrak Statrain train
    3. Take the bus from Gulfport to Fort Myersbus bus
    33h 39m
    $315–486

Lambert–St. Louis International Airport (STL) to Ft. Myers (RSW) flights

Calendar62Weekly Planes
Duration3h 58mAverage Duration
Ticket$133Cheapest Price
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Questions & Answers

Map of how to get from St. Louis to Sanibel.ExpandLaunch map view
  • Distance: 1,019 mi
  • Duration: 4h 38m

What companies run services between St. Louis, MO, USA and Sanibel, FL, USA?

Southwest Airlines, Delta, and American Airlines fly from Lambert–St. Louis International Airport (STL) to Ft. Myers (RSW) every 3 hours.

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