There are 4 ways to get from St. Louis to Sanibel by plane, bus (Flixbus, Greyhound), car, bus, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Lambert–St. Louis International Airport (STL) to Ft. Myers (RSW)plane STL - RSW
4h 28m$192–738Bus
- Take the bus from St Louis Bus Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Tampa Bus Stationbus
- Take the bus from Tampa Bus Station to Fort Myers Bus Stopbus
25h 18m$243–381Drive 1,123.7 mi
- Drive from St. Louis to Sanibelcar 1,123.7 mi
19h 22m$206–297Bus, train
- Take the bus from St Louis Bus Station to New Orleans Bus Stationbus
- Take the train from New Orleans Union Passenger Terminal to Gulfport Amtrak Statrain
- Take the bus from Gulfport to Fort Myersbus
33h 39m$342–472
Lambert–St. Louis International Airport (STL) to Ft. Myers (RSW) flights
Comparing Your Travel Options
The cheapest way to get from St. Louis to Sanibel is to drive which costs $200 - $300 and takes 19h 22m.
The fastest way to get from St. Louis to Sanibel is to fly which takes 4h 28m and costs $190 - $750.
No, there is no direct bus from St. Louis station to Sanibel. However, there are services departing from St Louis Bus Station and arriving at Fort Myers Bus Stop via Atlanta Bus Station and Tampa Bus Station. The journey, including transfers, takes approximately 25h 18m.
The distance between St. Louis and Sanibel is 1025 miles. The road distance is 1130.3 miles.
The best way to get from St. Louis to Sanibel without a car is to bus which takes 25h 18m and costs $240 - $390.
It takes approximately 4h 28m to get from St. Louis to Sanibel, including transfers.
St. Louis to Sanibel bus services, operated by Flixbus USA, depart from St Louis Bus Station.
The best way to get from St. Louis to Sanibel is to fly which takes 4h 28m and costs $190 - $750. Alternatively, you can bus, which costs $240 - $390 and takes 25h 18m.
St. Louis to Sanibel bus services, operated by Flixbus USA, arrive at Atlanta Bus Station.
Sanibel is 1h ahead of St. Louis. It is currently 1:32 AM in St. Louis and 2:32 AM in Sanibel.
What companies run services between St. Louis, MO, USA and Sanibel, FL, USA?
Southwest Airlines and Delta fly from Lambert–St. Louis International Airport (STL) to Ft. Myers (RSW) every 4 hours. Alternatively, you can take a bus from St Louis Bus Station to Sanibel via Atlanta Bus Station, Tampa Bus Station, and Fort Myers Bus Stop in around 25h 18m.
- Website
- southwest.com
Flights from Lambert–St. Louis International Airport to Ft. Myers
- Ave. Duration
- 2h 25m
- When
- Every day
- Estimated price
- $120–650
Flights from Lambert–St. Louis International Airport to Ft. Myers via Nashville
- Ave. Duration
- 4h 30m
- When
- Monday, Thursday, and Friday
- Estimated price
- $120–650
Flights from Lambert–St. Louis International Airport to Ft. Myers via Columbus
- Ave. Duration
- 4h 45m
- When
- Monday, Thursday, and Friday
- Estimated price
- $150–750
Flights from Lambert–St. Louis International Airport to Ft. Myers via Orlando
- Ave. Duration
- 4h 50m
- When
- Monday
- Estimated price
- $120–650
- Website
- delta.com
Flights from Lambert–St. Louis International Airport to Ft. Myers via Atlanta
- Ave. Duration
- 4h 7m
- When
- Every day
- Estimated price
- $120–650
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from New Orleans Union Passenger Terminal to Gulfport Amtrak Sta
- Ave. Duration
- 59 min
- Frequency
- Twice daily
- Estimated price
- $35–60
- Website
- Amtrak
- Phone
- +1 (855) 626-8585
- Website
- Flixbus USA
Bus from St Louis Bus Station to Atlanta Bus Station
- Ave. Duration
- 10h 10m
- Frequency
- 5 times a week
- Estimated price
- $85–130
- Schedules at
- Flixbus USA
Bus from Atlanta Bus Station to Tampa Bus Station
- Ave. Duration
- 9h 30m
- Frequency
- 5 times a week
- Estimated price
- $80–130
- Schedules at
- Flixbus USA
Bus from Tampa Bus Station to Fort Myers Bus Stop
- Ave. Duration
- 3h 5m
- Frequency
- 3 times a day
- Estimated price
- $21–35
- Schedules at
- Flixbus USA
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- [email protected]
- Website
- Greyhound
Bus from St Louis Bus Station to Atlanta Bus Station
- Ave. Duration
- 11h 40m
- Frequency
- Once daily
- Estimated price
- $95–150
- Website
- Greyhound
Bus from St Louis Bus Station to New Orleans Bus Station
- Ave. Duration
- 16h 50m
- Frequency
- Once daily
- Estimated price
- $120–190
- Website
- Greyhound
- Phone
- +1 800-923-1799
- [email protected]
- Website
- Omnibus Express
Bus from Gulfport to Fort Myers
- Ave. Duration
- 13h 17m
- Frequency
- Once daily
- Estimated price
- $120–150
- Schedules at
- Omnibus Express
Want to know more about travelling around United States
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Booking & Getting There
Yes, the driving distance between St. Louis to Sanibel is 1130 miles. It takes approximately 19h 22m to drive from St. Louis to Sanibel.
There are 3673+ hotels available in Sanibel.