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How to get fromSt. Louis to Sanibelby plane, bus (Greyhound, Flixbus), car, taxi, bus, or train

Find Transport to Sanibel

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There are 5 ways to get from St. Louis to Sanibel by plane, bus (Greyhound, Flixbus), car, taxi, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Lambert–St. Louis International Airport to Ft. Myers

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to Ft. Myers (RSW)plane plane STL - RSW
    4h 33m
    $192–738

  2. Bus

    1. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta Bus Station to Tampa Bus Stationbus bus
    3. Take the bus from Tampa Bus Station to Fort Myers Bus Stopbus bus
    26h 28m
    $232–358

  3. Drive  1,123.7 mi

    1. Drive from St. Louis to Sanibelcar car 1,123.7 mi
    19h 22m
    $206–297

  4. Fly Midamerica St. Louis Airport to Punta Gorda Airport, taxi

    1. Fly from Midamerica St. Louis Airport (BLV) to Punta Gorda Airport (PGD)plane plane BLV - PGD
    2. Take the taxi from Punta Gorda Airport (PGD) to Sanibeltaxi taxi
    5h 20m
    $220–610

  5. Bus, train

    1. Take the bus from St Louis Bus Station to New Orleans Bus Stationbus bus
    2. Take the train from New Orleans Union Passenger Terminal to Gulfport Amtrak Statrain train
    3. Take the bus from Gulfport to Fort Myersbus bus
    33h 39m
    $307–438

Lambert–St. Louis International Airport (STL) to Ft. Myers (RSW) flights

Calendar76Weekly Planes
Duration4h 6mAverage Duration
Ticket$123Cheapest Price
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Comparing Your Travel Options

Map of how to get from St. Louis to Sanibel.ExpandLaunch map view
  • Distance: 1,019 mi
  • Duration: 4h 33m

What companies run services between St. Louis, MO, USA and Sanibel, FL, USA?

Southwest Airlines and Delta fly from Lambert–St. Louis International Airport (STL) to Ft. Myers (RSW) every 2 hours. Alternatively, you can take a bus from St Louis Bus Station to Sanibel via Atlanta Bus Station, Tampa Bus Station, and Fort Myers Bus Stop in around 26h 28m.

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