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How to get fromSt. Louis to Senecaby plane, taxi, bus, or car

Find Transport to Seneca

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There are 6 ways to get from St. Louis to Seneca by plane, taxi, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Greenville–Spartanburg International Airport, taxi

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to Greenville–Spartanburg International Airport (GSP)plane plane STL - GSP
    2. Take the taxi from Greenville–Spartanburg International Airport (GSP) to Senecataxi taxi
    5h 48m
    $252–872

  2. Fly to Asheville Regional Airport, drive

    cheapest
    1. Fly from Lambert–St. Louis International Airport (STL) to Asheville Regional Airport (AVL)plane plane STL - AVL
    2. Drive from Asheville-Airport-AVL to Senecacar car
    7h 3m
    $104–512

  3. Bus, taxi

    1. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus
    2. Take the bus from Atlanta to Flying J - Commercebus bus
    3. Take the taxi from Flying J - Commerce to Senecataxi taxi
    14h 52m
    $231–440

  4. Drive 611 mi

    1. Drive from St. Louis to Senecacar car 611 mi
    10h 58m
    $112–162

  5. Fly to Hartsfield-Jackson Atlanta International Airport, bus, taxi

    1. Fly from Lambert–St. Louis International Airport (STL) to Hartsfield-Jackson Atlanta International Airport (ATL)plane plane STL - ATL
    2. Take the bus from Atlanta to Flying J - Commercebus bus
    3. Take the taxi from Flying J - Commerce to Senecataxi taxi
    7h 37m
    $246–876

  6. Bus, taxi via Evansville

    1. Take the bus from St Louis Bus Station to Evansville Bus Stationbus bus
    2. Take the bus from Evansville Bus Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta to Flying J - Commercebus bus
    4. Take the taxi from Flying J - Commerce to Senecataxi taxi
    16h 47m
    $255–467

Lambert–St. Louis International Airport (STL) to Greenville–Spartanburg International Airport (GSP) flights

Calendar126Weekly Planes
Duration4h 44mAverage Duration
Ticket$126Cheapest Price
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Questions & Answers

Map of how to get from St. Louis to Seneca.ExpandLaunch map view
  • Distance: 586.5 mi
  • Duration: 5h 48m

What companies run services between St. Louis, MO, USA and Seneca, SC, USA?

There is no direct connection from St. Louis to Seneca. However, you can take the train to LAMBERT AIRPORT TERMINAL #1 station, walk to Lambert–St. Louis International Airport (STL) airport, fly to Greenville–Spartanburg International Airport (GSP), then take the taxi to Seneca. Alternatively, you can take the bus to Atlanta Bus Station, walk to Garnett Station, take the subway to Doraville Station, walk to Atlanta, take the bus to Flying J - Commerce, then take the taxi to Seneca.

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