Rome2Rio

How to get fromSt. Louis to Sioux Fallsby plane, bus (Greyhound), train, bus, or car

Find Transport to Sioux Falls

See all options

There are 5 ways to get from St. Louis to Sioux Falls by plane, bus (Greyhound), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Lambert–St. Louis International Airport

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to Sioux Falls (FSD)plane plane STL - FSD
    6h 39m
    $94–494

  2. Bus

    1. Take the bus from St Louis Bus Station to Des Moinesbus bus
    2. Take the bus from Des Moines to Omaha, NEbus bus
    3. Take the bus from Omaha to Sioux Fallsbus bus
    18h 18m
    $140–247

  3. Train, bus

    1. Take the train from St. Louis to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to St. Paul-Minneapolistrain train
    3. Take the bus from Burnsville to Sioux Fallsbus bus
    21h 20m
    $304–574

  4. Drive 607.2 mi

    1. Drive from St. Louis to Sioux Fallscar car 607.2 mi
    9h 59m
    $111–161

  5. Train to Abraham Lincoln Capital Airport, fly

    1. Take the train from St. Louis to Springfieldtrain train
    2. Fly from Abraham Lincoln Capital Airport (SPI) to Sioux Falls (FSD)plane plane SPI - FSD
    9h 33m
    $116–451

Lambert–St. Louis International Airport (STL) to Sioux Falls (FSD) flights

Calendar134Weekly Planes
Duration5h 38mAverage Duration
Ticket$94Cheapest Price
See schedules

Questions & Answers

Map of how to get from St. Louis to Sioux Falls.ExpandLaunch map view
  • Distance: 490.1 mi
  • Duration: 6h 39m

What companies run services between St. Louis, MO, USA and Sioux Falls, SD, USA?

Delta, American Airlines, and United Airlines fly from Lambert–St. Louis International Airport (STL) to Sioux Falls (FSD) hourly. Alternatively, you can take a bus from St Louis Bus Station to The Bus Stop via Des Moines, Omaha, Sioux Falls, and Maple/Career NE corner in around 18h 18m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers